Evidence map›Paper›PMID 29535195›Full record

ArticlemBio2018

Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine.

Lisa K McNeil, Robert G K Donald, Alexey Gribenko, Roger French, Nathaniel Lambert, Shannon L Harris, Thomas R Jones, Sheng Li, Gary Zlotnick, Ulrich Vogel and 16 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2020
    Guideline
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  19. US College Students Are at Increased Risk for Serogroup B Meningococcal Disease.Journal of the Pediatric Infectious Diseases Society · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 7 countries.

Lisa K McNeilPfizer Vaccine Research and Development, Pearl River, New York, USA.
Robert G K DonaldPfizer Vaccine Research and Development, Pearl River, New York, USA.
Alexey GribenkoPfizer Vaccine Research and Development, Pearl River, New York, USA.
Roger FrenchPfizer Vaccine Research and Development, Pearl River, New York, USA.
Nathaniel LambertPfizer Vaccine Research and Development, Pearl River, New York, USA.
Shannon L HarrisPfizer Vaccine Research and Development, Pearl River, New York, USA.
Thomas R JonesPfizer Vaccine Research and Development, Pearl River, New York, USA.
Sheng LiDepartment of Medicine, University of California, San Diego, California, USA.
Gary ZlotnickPfizer Vaccine Research and Development, Pearl River, New York, USA.
Ulrich VogelInstitute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Heike ClausInstitute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Raquel AbadReference and Research Laboratory for Vaccine Preventable Bacterial Diseases, Institute of Health Carlos III, Majadahonda, Spain.
Julio A VazquezReference and Research Laboratory for Vaccine Preventable Bacterial Diseases, Institute of Health Carlos III, Majadahonda, Spain.
Ray BorrowPublic Health England, Manchester Royal Infirmary, Manchester, United Kingdom.
Jamie FindlowPublic Health England, Manchester Royal Infirmary, Manchester, United Kingdom.
Muhamed-Kheir TahaInstitut Pasteur, Invasive Bacterial Infections Unit, Paris, France.ORCID 0000-0002-0716-3174
Ala-Eddine DeghmaneInstitut Pasteur, Invasive Bacterial Infections Unit, Paris, France.
Dominique A CaugantDepartment of Bacteriology and Immunology, Norwegian Institute of Public Health, Oslo, Norway.
Paula KrizNational Institute of Public Health, Prague, Czech Republic.
Martin MusilekNational Institute of Public Health, Prague, Czech Republic.
Xin WangMeningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jeni VuongMeningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Leonard W MayerMeningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Michael W PridePfizer Vaccine Research and Development, Pearl River, New York, USA.
Kathrin U JansenPfizer Vaccine Research and Development, Pearl River, New York, USA.
Annaliesa S AndersonPfizer Vaccine Research and Development, Pearl River, New York, USA Annaliesa.anderson@pfizer.com.
Pfizer (United States) · USCenters for Disease Control and Prevention · USInstituto de Salud Carlos III · ESInstitut Pasteur · FRManchester Royal Infirmary · GBNational Institute of Public Health · CZUniversity of Würzburg · DENorwegian Institute of Public Health · NOUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bivalent rLP2086 (Trumenba), a vaccine for prevention of

Indexed as

Anti-Bacterial AgentsAntibodies, BacterialAntigens, BacterialBacterial ProteinsBlood Bactericidal ActivityFlow CytometryHumansMeningococcal VaccinesMicrobial ViabilityNeisseria meningitidis, Serogroup BAnti-Bacterial AgentsAntibodies, BacterialAntigens, BacterialBacterial Proteinsfactor H-binding protein, Neisseria meningitidisMeningococcal Vaccinesfactor H binding proteinflow cytometrymeningococcal antigen surface expression (MEASURE) assayNeisseria meningitidis serogroup Bvaccine

Identifiers

PMID29535195
PMCPMC5850321
OpenAlexW2791363799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.