ArticleJournal of the American Heart Association2018
Predictors and Prognostic Value of Worsening Renal Function During Admission in HFpEF Versus HFrEF: Data From the KorAHF (Korean Acute Heart Failure) Registry.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01389843 (Registry), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Registry (Prospective Cohort) for Heart Failure in Korea (KorAHF)
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effect of carperitide on clinical outcomes among patients with acute heart failure: a meta-analysis of randomized and propensity‑matched studies.BMC cardiovascular disorders · 2025Pooled it
- Implantable Cardioverter-defibrillator Utilization and Its Outcomes in Korea: Data from Korean Acute Heart Failure Registry.Journal of Korean medical science · 2020Trial
- Acute Heart Failure in Heart Failure with Preserved Ejection Fraction: A State-of-the-art Review from an International Expert Group.Cardiac failure review · 2026Review
- Article
- J-shaped relationship between serum creatinine and mortality in Korean patients with acute heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Observational
- Biomarkers in Heart Failure with Preserved Ejection Fraction: A Perpetually Evolving Frontier.Journal of clinical medicine · 2024Review
- Worsening Renal Function and Adverse Outcomes in Patients with HFpEF with or without Atrial Fibrillation.Biomedicines · 2023Article
- Prediction of Outcomes Through Cystatin C and cTnI in Elderly Type 2 Myocardial Infarction Patients.Clinical interventions in aging · 2023Article
- Risk factors of short-term, intermediate-term, and long-term cardiac events in patients hospitalized for HFmrEF.ESC heart failure · 2022Article
- Insulin-like growth factor-1 (IGF-1) as predictor of cardiovascular mortality in heart failure patients: data from the T.O.S.CA. registry.Internal and emergency medicine · 2022Article
- Multimorbidity, guideline-directed medical therapies, and associated outcomes among hospitalized heart failure patients.ESC heart failure · 2022Article
- Prognostic and Therapeutic Implications of Renal Insufficiency in Heart Failure.International journal of heart failure · 2022Review
- Phenomapping in patients experiencing worsening renal function during hospitalization for acute heart failure.ESC heart failure · 2021Article
- The Prognostic Impact of Estimated Creatinine Clearance by Bioelectrical Impedance Analysis in Heart Failure: Comparison of Different eGFR Formulas.Biomedicines · 2021Article
- Acute Decompensated Heart Failure and the Kidney: Physiological, Histological and Transcriptomic Responses to Development and Recovery.Journal of the American Heart Association · 2021Article
- Clinical Impact of Worsening Renal Function in Elderly Patients with Acute Decompensated Heart Failure.International journal of heart failure · 2021Article
- Worsening Renal Function during Acute Decompensated Heart Failure: A Bad Signal Never to Ignore.International journal of heart failure · 2021Article
- Renal dysfunction in cardiovascular diseases and its consequences.Journal of nephrology · 2021Review
- Potential Mechanisms of SGLT2 Inhibitors for the Treatment of Heart Failure With Preserved Ejection Fraction.Frontiers in physiology · 2021Review
- Paradigm Shifts of Heart Failure Therapy: Do We Need Another Paradigm?International journal of heart failure · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWorsening renal function (WRF) is associated with adverse outcomes in patients with heart failure. We investigated the predictors and prognostic value of WRF during admission, in patients with preserved ejection fraction (HFpEF) versus those with reduced ejection fraction (HFrEF). METHODS AND
resultsA total of 5625 patients were enrolled in the KorAHF (Korean Acute Heart Failure) registry. WRF was defined as an absolute increase in creatinine of ≥0.3 mg/dL. Transient WRF was defined as recovery of creatinine at discharge, whereas persistent WRF was indicated by a nonrecovered creatinine level. HFpEF and HFrEF were defined as a left ventricle ejection fraction ≥50% and ≤40%, respectively. Among the total population, WRF occurred in 3101 patients (55.1%). By heart failure subgroup, WRF occurred more frequently in HFrEF (57.0% versus 51.3%;
conclusionsIn patients with acute heart failure patients, WRF is an independent predictor of adverse in-hospital and follow-up outcomes in both HFrEF and HFpEF, though with a different effect size. CLINICAL
trial registrationURL: https://www.clinicaltrials.gov. Unique identifier: NCT01389843.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.