ArticleThe Annals of thoracic surgery2018
Radiographic Predictors of Resectability in Thymic Carcinoma.
Article in The Annals of thoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Myasthenia Gravis and Thymoma.Muscle & nerve · 2026Review
- Article
- Re-evaluation and operative indications after induction therapy for thymic epithelial tumors.Mediastinum (Hong Kong, China) · 2024Review
- Update on thymic epithelial tumors: a narrative review.Mediastinum (Hong Kong, China) · 2024Review
- Conventional and radiomic features to predict pathology in the preoperative assessment of anterior mediastinal masses.Lung cancer (Amsterdam, Netherlands) · 2023Article
- Review
- Prognostic CT features in patients with untreated thymic epithelial tumors.Scientific reports · 2023Article
- Risk factor analysis for major mediastinal vessel invasion in thymic epithelial tumors based on multi-slice CT Imaging.Frontiers in oncology · 2023Article
- Using CT to evaluate mediastinal great vein invasion by thymic epithelial tumors: measurement of the interface between the tumor and neighboring structures.European radiology · 2022Article
- CT Radiomic Features for Predicting Resectability and TNM Staging in Thymic Epithelial Tumors.The Annals of thoracic surgery · 2022Article
- Elevated serum CYFRA 21-1 level as a diagnostic marker for thymic carcinoma.Thoracic cancer · 2021Article
- Acute Angle of Multilobulated Contours Improves the Risk Classification of Thymomas.Frontiers in medicine · 2021Article
- Superior Vena Cava Resection in Locally Advanced Thymoma-Surgical and Survival Outcomes.Indian journal of surgical oncology · 2020Article
- The usefulness of radiographic imaging for predicting the resectability of thymic carcinoma.Journal of thoracic disease · 2018Article
- Morphological assessment of thymic carcinoma through imaging: is computed tomography useful in selecting patients for surgery and in predicting incomplete resection?Journal of thoracic disease · 2018Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe aim of this study was to assess preoperative computed tomography characteristics of thymic carcinomas and to investigate which features could predict an incomplete surgical resection. A secondary aim was to correlate preoperative imaging features with Masaoka stage.
methodsIn this study, approved by our Institutional Review Board, two readers retrospectively reviewed preoperative computed tomography scans at our tertiary referral oncology center between 1994 and 2014. Imaging features analyzed included tumor morphology, infiltration of surrounding mediastinal fat, loss of surrounding fat plane, degree of contact between tumor and great vessels, and associated pulmonary or pleural abnormality. Surgical and pathologic records were reviewed for completeness of surgical resection and Masaoka stage.
resultsForty-one patients were included, with Masaoka stage I (n = 3), stage II (n = 4), stage III (n = 12), and stage IV (n = 22). Twenty-one patients (51%) had a complete surgical resection. Ten had microscopic residual disease (R1) with involved surgical margins at pathology, and 10 patients had macroscopic residual disease (R2) at surgery. In addition to lesion size, the feature associated with incomplete surgical resection was the degree of tumor contact with adjacent mediastinal vessels on the preoperative computed tomography image (p = 0.038). Many of the more common features associated with incomplete resection were also more likely to be present in patients with late Masaoka stage (III/IV), including infiltration of the mediastinal fat, which was present in all 34 patients with Masaoka stage III/IV compared with 5 patients (71%) with stage I/II (p = 0.03).
conclusionsPreoperative computed tomography imaging features may help to identify patients at risk for an incomplete surgical resection.
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