ArticleEpidemiology and infection2018
Seasonality and within-subject clustering of rotavirus infections in an eight-site birth cohort study.
Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Investigating seasonal patterns in enteric infections: a systematic review of time series methods.Epidemiology and infection · 2022Pooled it
- Clinical and nutritional correlates of bacterial diarrhoea aetiology in young children: a secondary cross-sectional analysis of the ABCD trial.BMJ paediatrics open · 2024Trial
- Etiology and Incidence of Moderate-to-Severe Diarrhea in Young Children in Niger.Journal of the Pediatric Infectious Diseases Society · 2021Trial
- Review
- Article
- Epidemiological, molecular, and evolutionary characteristics of G1P[8] rotavirus in China on the eve of RotaTeq application.Frontiers in cellular and infection microbiology · 2024Article
- Delineating the Seasonality of Varicella and Its Association With Climate in the Tropical Country of Colombia.The Journal of infectious diseases · 2023Article
- Seasonal variation of diarrhoeal pathogens among Guinea-Bissauan children under five years of age.PLoS neglected tropical diseases · 2023Article
- Burden, Clinical Characteristics, Risk Factors, and Seasonality of Adenovirus 40/41 Diarrhea in Children in Eight Low-Resource Settings.Open forum infectious diseases · 2022Article
- Article
- Prevalence of diarrhoeal pathogens among children under five years of age with and without diarrhoea in Guinea-Bissau.PLoS neglected tropical diseases · 2021Article
- Pathogen-Specific Impacts of the 2011-2012 La Niña-Associated Floods on Enteric Infections in the MAL-ED Peru Cohort: A Comparative Interrupted Time Series Analysis.International journal of environmental research and public health · 2020Article
- Rotavirus Seasonality: An Application of Singular Spectrum Analysis and Polyharmonic Modeling.International journal of environmental research and public health · 2019Article
- Consultations for gastroenteritis in general practice and out-of-hours services in Norway 2006-15.Family practice · 2019Article
- The seasonality of diarrheal pathogens: A retrospective study of seven sites over three years.PLoS neglected tropical diseases · 2019Article
- Use of earth observation-derived hydrometeorological variables to model and predict rotavirus infection (MAL-ED): a multisite cohort study.The Lancet. Planetary health · 2019Article
- Rates of hospitalization and death for all-cause and rotavirus acute gastroenteritis before rotavirus vaccine introduction in Kenya, 2010-2013.BMC infectious diseases · 2019Article
- Evaluating meteorological data from weather stations, and from satellites and global models for a multi-site epidemiological study.Environmental research · 2018Article
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improving understanding of the pathogen-specific seasonality of enteric infections is critical to informing policy on the timing of preventive measures and to forecast trends in the burden of diarrhoeal disease. Data obtained from active surveillance of cohorts can capture the underlying infection status as transmission occurs in the community. The purpose of this study was to characterise rotavirus seasonality in eight different locations while adjusting for age, calendar time and within-subject clustering of episodes by applying an adapted Serfling model approach to data from a multi-site cohort study. In the Bangladesh and Peru sites, within-subject clustering was high, with more than half of infants who experienced one rotavirus infection going on to experience a second and more than 20% experiencing a third. In the five sites that are in countries that had not introduced the rotavirus vaccine, the model predicted a primary peak in prevalence during the dry season and, in three of these, a secondary peak during the rainy season. The patterns predicted by this approach are broadly congruent with several emerging hypotheses about rotavirus transmission and are consistent for both symptomatic and asymptomatic rotavirus episodes. These findings have practical implications for programme design, but caution should be exercised in deriving inferences about the underlying pathways driving these trends, particularly when extending the approach to other pathogens.
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