Evidence map›Paper›PMID 29534536›Full record

ArticleMolecules (Basel, Switzerland)2018

Lung Cancer Chemopreventive Activity of Patulin Isolated from Penicillium vulpinum.

Aymeric Monteillier, Pierre-Marie Allard, Katia Gindro, Jean-Luc Wolfender, Muriel Cuendet

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Cytochalasans from the Endophytic FungusJournal of fungi (Basel, Switzerland) · 2022
    Article
  6. Review
  7. Review
  8. Identification of Patulin fromMolecules (Basel, Switzerland) · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aymeric MonteillierSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland. aymeric.monteillier@unige.ch.
Pierre-Marie AllardSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland. pierre-marie.allard@unige.ch.ORCID 0000-0003-3389-2191
Katia GindroMycology and Biotechnology group, Plant, Agroscope, Route de Duillier 60, P.O. Box 1012, 1260 Nyon, Switzerland. katia.gindro@agroscope.admin.ch.
Jean-Luc WolfenderSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland. jean-luc.wolfender@unige.ch.
Muriel CuendetSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland. muriel.cuendet@unige.ch.ORCID 0000-0002-1523-1907
University of Geneva · CHAgroscope · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most lethal form of cancer in the world. Its development often involves an overactivation of the nuclear factor kappa B (NF-κB) pathway, leading to increased cell proliferation, survival, mobility, and a decrease in apoptosis. Therefore, NF-κB inhibitors are actively sought after for both cancer chemoprevention and therapy, and fungi represent an interesting unexplored reservoir for such molecules. The aim of the present work was to find naturally occurring lung cancer chemopreventive compounds by investigating the metabolites of

Indexed as

A549 CellsAntineoplastic AgentsCell ProliferationCell SurvivalDown-RegulationDrug Screening Assays, AntitumorGene Expression Regulation, NeoplasticHEK293 CellsHumansLung NeoplasmsPatulinPenicilliumSignal TransductionTranscription Factor RelATumor Necrosis Factor-alphaAntineoplastic AgentsPatulinRELA protein, humanTNF protein, humanTranscription Factor RelATumor Necrosis Factor-alphacancer chemopreventionNF-κBpatulinPenicillium vulpinumWnt

Identifiers

PMID29534536
PMCPMC6017800
OpenAlexW2791688103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.