Evidence map›Paper›PMID 29534533›Full record

ArticleInternational journal of molecular sciences2018

3'-UTR Polymorphisms of MTHFR and TS Associated with Osteoporotic Vertebral Compression Fracture Susceptibility in Postmenopausal Women.

Tae-Keun Ahn, Jung Oh Kim, Hyun Woo Kim, Han Sung Park, Jeong Hyun Shim, Alexander E Ropper, In Bo Han, Nam Keun Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Role of Epigenomics in Osteoporosis and Osteoporotic Vertebral Fracture.International journal of molecular sciences · 2020
    Review
  6. Article
  7. Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.International journal of molecular sciences · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Tae-Keun AhnDepartment of Orthopedics, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea. ajh329@gmail.com.ORCID 0000-0001-9177-1692
Jung Oh KimDepartment of Biomedical Science, College of Life Science, CHA University, Seongnam 13488, Korea. jokim8505@gmail.com.
Hyun Woo KimDepartment of Biomedical Science, College of Life Science, CHA University, Seongnam 13488, Korea. woowoo17@naver.com.
Han Sung ParkDepartment of Biomedical Science, College of Life Science, CHA University, Seongnam 13488, Korea. hahnsung@naver.com.
Jeong Hyun ShimDepartment of Neurosurgery, Shim Jeong Hospital, Seoul 08761, Korea. gumjung70@gmail.com.
Alexander E RopperDepartment of Neurosurgery, Baylor Colleage of Medicine, Houston, TX 77030, USA. aropper@gmail.com.
In Bo HanDepartment of Neurosurgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea. hanib@cha.ac.kr.ORCID 0000-0002-0834-9325
Nam Keun KimDepartment of Biomedical Science, College of Life Science, CHA University, Seongnam 13488, Korea. nkkim@cha.ac.kr.ORCID 0000-0003-0541-3528
CHA University · KRCHA University Bundang Medical Center · KRBaylor College of Medicine · USJeju National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmenopausal osteoporosis is one of the most prominent diseases in postmenopausal women and it is increasing in prevalence with the aging population. Furthermore, osteoporosis and osteoporotic vertebral compression fractures (OVCFs) are related to mortality and decreased quality of life. Therefore, searching for biomarkers that are able to identify postmenopausal women who are at high risk of developing OVCFs is an effective strategy for improving the quality of life of patients and alleviating social and economic burdens. In this study, we investigated methylenetetrahydrofolate reductase (

Indexed as

Polymorphism, Single Nucleotide3' Untranslated RegionsAgedCase-Control StudiesFemaleFractures, CompressionHumansMethylenetetrahydrofolate Reductase (NADPH2)Middle AgedOsteoporosis, PostmenopausalOsteoporotic FracturesSpinal FracturesThymidylate Synthase3' Untranslated RegionsMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanThymidylate Synthasecompression fracturemethylenetetrahydrofolate reductaseosteoporosispolymorphismthymidylate synthase

Identifiers

PMID29534533
PMCPMC5877685
OpenAlexW2791264912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.