Evidence map›Paper›PMID 29534058›Full record

ArticleScientific data2018

Pediatric patients at risk for fever in chemotherapy-induced neutropenia in Bern, Switzerland, 1993-2012.

Annina N von Allmen, Maxime G Zermatten, Kurt Leibundgut, Philipp Agyeman, Roland A Ammann

Abstract readDataset
In one paragraph

Article in Scientific data, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Diagnostic and Therapeutic Challenge Caused byPathogens (Basel, Switzerland) · 2024
    Review
  2. Etiology and Factors Affecting Severe Complications and Mortality of Febrile Neutropenia in Children with Acute LeukemiaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annina N von AllmenDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Maxime G ZermattenDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Kurt LeibundgutDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Philipp AgyemanDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Roland A AmmannDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fever in neutropenia (FN) is the most frequent potentially life threatening complication of chemotherapy for cancer. Prediction of the risk to develop FN during chemotherapy would allow for targeted prophylaxis. This retrospective, single centre cohort study in pediatric patients diagnosed with cancer before 17 years covered two decades, 1993 to 2012. The 583 (73%) of 800 patients diagnosed with cancer who had received chemotherapy were studied here. Data on 2113 observation periods was collected, defined by stable combinations of 11 predefined characteristics potentially associated with FN. They covered 692 years of cumulative chemotherapy exposure time, during which 712 FN episodes were diagnosed, 154 (22%) of them with bacteremia. The risk to develop FN and FN with bacteremia remained stable over time. These data can mainly be used to study FN risks over time and between centers, and to derive or externally validate FN risk prediction rules.

Indexed as

FeverNeutropeniaAdolescentAntineoplastic AgentsChildFemaleHumansMaleNeoplasmsRetrospective StudiesRiskSwitzerlandAntineoplastic Agents

Identifiers

PMID29534058
PMCPMC5849221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.