Evidence map›Paper›PMID 29534053›Full record

ReviewBiosensors2018

Calibration of Minimally Invasive Continuous Glucose Monitoring Sensors: State-of-The-Art and Current Perspectives.

Giada Acciaroli, Martina Vettoretti, Andrea Facchinetti, Giovanni Sparacino

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Continuous glucose monitoring in type 2 diabetes: a systematic review of barriers and opportunities for care improvement.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025
    Pooled it
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  5. Observational
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  16. Two-Dimensional TiBiosensors · 2022
    Article
  17. Review
  18. Review
  19. Continuous Glucose Monitoring in the Hospital.Endocrinology and metabolism (Seoul, Korea) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giada AcciaroliDepartment of Information Engineering, University of Padova, 35131 Padova, Italy. giada.acciaroli@phd.unipd.it.
Martina VettorettiDepartment of Information Engineering, University of Padova, 35131 Padova, Italy. vettore1@dei.unipd.it.
Andrea FacchinettiDepartment of Information Engineering, University of Padova, 35131 Padova, Italy. facchine@dei.unipd.it.ORCID 0000-0001-8041-2280
Giovanni SparacinoDepartment of Information Engineering, University of Padova, 35131 Padova, Italy. gianni@dei.unipd.it.ORCID 0000-0002-3248-1393
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive continuous glucose monitoring (CGM) sensors are wearable medical devices that provide real-time measurement of subcutaneous glucose concentration. This can be of great help in the daily management of diabetes. Most of the commercially available CGM devices have a wire-based sensor, usually placed in the subcutaneous tissue, which measures a "raw" current signal via a glucose-oxidase electrochemical reaction. This electrical signal needs to be translated in real-time to glucose concentration through a calibration process. For such a scope, the first commercialized CGM sensors implemented simple linear regression techniques to fit reference glucose concentration measurements periodically collected by fingerprick. On the one hand, these simple linear techniques required several calibrations per day, with the consequent patient's discomfort. On the other, only a limited accuracy was achieved. This stimulated researchers to propose, over the last decade, more sophisticated algorithms to calibrate CGM sensors, resorting to suitable signal processing, modelling, and machine-learning techniques. This review paper will first contextualize and describe the calibration problem and its implementation in the first generation of CGM sensors, and then present the most recently-proposed calibration algorithms, with a perspective on how these new techniques can influence future CGM products in terms of accuracy improvement and calibration reduction.

Indexed as

AlgorithmsAnimalsBiosensing TechniquesBlood GlucoseBlood Glucose Self-MonitoringCalibrationDiabetes MellitusHumansBlood Glucosecalibrationcontinuous glucose monitoringdiabetesglucose sensors

Identifiers

PMID29534053
PMCPMC5872072
OpenAlexW2793983546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.