Evidence map›Paper›PMID 29534033›Full record

ArticleInternational journal of molecular sciences2018

Structure/Function Analysis of Cotton-Based Peptide-Cellulose Conjugates: Spatiotemporal/Kinetic Assessment of Protease Aerogels Compared to Nanocrystalline and Paper Cellulose.

J Vincent Edwards, Krystal Fontenot, Falk Liebner, Nicole Doyle Nee Pircher, Alfred D French, Brian D Condon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
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  6. Review
  7. Synthesis and Applications of Biopolymer Composites.International journal of molecular sciences · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

J Vincent EdwardsSouthern Regional Research Center, USDA, New Orleans, LA 70124, USA. vince.edwards@ars.usda.gov.
Krystal FontenotSouthern Regional Research Center, USDA, New Orleans, LA 70124, USA. krystal.fontenot@ars.usda.gov.
Falk LiebnerUniversity of Natural Resources and Life Sciences Vienna, Konrad-Lorenz-Straße 24, A-3430 Tulln an der Donau, Austria. falk.liebner@boku.ac.at.
Nicole Doyle Nee PircherUniversity of Natural Resources and Life Sciences Vienna, Konrad-Lorenz-Straße 24, A-3430 Tulln an der Donau, Austria. nicole.pircher@boku.ac.at.
Alfred D FrenchSouthern Regional Research Center, USDA, New Orleans, LA 70124, USA. Al.French@ars.usda.gov.
Brian D CondonSouthern Regional Research Center, USDA, New Orleans, LA 70124, USA. brian.condon@ars.usda.gov.
Southern Regional Research Center · USBOKU University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanocellulose has high specific surface area, hydration properties, and ease of derivatization to prepare protease sensors. A Human Neutrophil Elastase sensor designed with a nanocellulose aerogel transducer surface derived from cotton is compared with cotton filter paper, and nanocrystalline cellulose versions of the sensor. X-ray crystallography was employed along with Michaelis-Menten enzyme kinetics, and circular dichroism to contrast the structure/function relations of the peptide-cellulose conjugate conformation to enzyme/substrate binding and turnover rates. The nanocellulosic aerogel was found to have a cellulose II structure. The spatiotemporal relation of crystallite surface to peptide-cellulose conformation is discussed in light of observed enzyme kinetics. A higher substrate binding affinity (

Indexed as

BiocatalysisBiosensing TechniquesCelluloseGelsGossypiumHumansLeukocyte ElastaseNanoparticlesPeptidesProtein BindingStructure-Activity RelationshipCelluloseGelsLeukocyte ElastasePeptidesaerogelhuman neutrophil elastasenanocellulosepeptide-cellulose conformationprotease sensor

Identifiers

PMID29534033
PMCPMC5877701
OpenAlexW2792215155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.