Evidence map›Paper›PMID 29533727›Full record

ArticleJournal of dental research2018

Reduced Orthodontic Tooth Movement in Enpp1 Mutant Mice with Hypercementosis.

M Wolf, M Ao, M B Chavez, T N Kolli, V Thumbigere-Math, K Becker, E Y Chu, A Jäger, M J Somerman, B L Foster

Abstract readComparative Study
In one paragraph

Article in Journal of dental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. The NLRP3 Inflammasome Regulates Orthodontic Tooth Movement.Orthodontics & craniofacial research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Standardized assessment of bone micromorphometry around teeth following orthodontic tooth movement : A µCT split-mouth study in mice.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2022
    Article
  9. [Cells · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

M Wolf1 Department of Orthodontics, Aachen University, Aachen, Germany.
M Ao2 National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
M B Chavez3 Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
T N Kolli3 Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
V Thumbigere-Math2 National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
K Becker5 Department of Orthodontics, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
E Y Chu2 National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
A Jäger6 Department of Orthodontics, University of Bonn, Bonn, Germany.
M J Somerman2 National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
B L Foster3 Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
National Institute of Arthritis and Musculoskeletal and Skin Diseases · USThe Ohio State University · USHeinrich Heine University Düsseldorf · DEUniversity of Bonn · DEUniversity of Maryland, Baltimore · US

Funding

NIAMS Light Imaging FacilityZICAR041186 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI RANDAZZO, DAVIDE · 2010 to 2025
$18.2M
Laboratory of Oral Connective Tissue BiologyZIAAR041196 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI SOMERMAN, MARTHA · 2013 to 2021
$8.9M
Extracellular Matrix and Phosphate/Pyrophosphate Metabolism in Cementum FormationR00AR066110 · NIAMS · OHIO STATE UNIVERSITY · PI FOSTER, BRIAN LEE · 2015 to 2017
$747k
NIAMS NIH HHS R00 AR066110
6 · The paper itself

Abstract

Previous studies revealed that cementum formation is tightly regulated by inorganic pyrophosphate (PP

Indexed as

AnimalsDental CementumHypercementosisImmunohistochemistryMiceOsteoclastsPeriodontal LigamentPhosphoric Diester HydrolasesPyrophosphatasesRoot ResorptionTartrate-Resistant Acid PhosphataseTooth Movement TechniquesX-Ray Microtomographyectonucleotide pyrophosphatase phosphodiesterase 1Phosphoric Diester HydrolasesPyrophosphatasesTartrate-Resistant Acid Phosphatasebonedental cementumdentinorthodonticsosteoclaststooth calcification

Identifiers

PMID29533727
PMCPMC6728553
OpenAlexW2791539711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.