Evidence map›Paper›PMID 29533008›Full record

ArticleCancer medicine2018

Genomic complexity in pediatric synovial sarcomas (Synobio study): the European pediatric soft tissue sarcoma group (EpSSG) experience.

Daniel Orbach, Véronique Mosseri, Daniel Pissaloux, Gaelle Pierron, Bernadette Brennan, Andrea Ferrari, Frederic Chibon, Gianni Bisogno, Gian Luca De Salvo, Camille Chakiba and 4 more

Abstract read
In one paragraph

Article in Cancer medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Synovial Sarcoma: Molecular Biology, Pathology, and Therapeutic Strategies.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Synovial Sarcoma in Children, Adolescents, and Young Adults: A Report From the Children's Oncology Group ARST0332 Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Article
  11. The clear cell sarcoma functional genomic landscape.The Journal of clinical investigation · 2021
    Article
  12. Article
  13. Article
  14. Systemic therapy in pediatric-type soft-tissue sarcoma.Current oncology (Toronto, Ont.) · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel OrbachSIREDO oncology center (Care, Innovation and Research for Children, Adolescents and Young Adults with cancer), Institut Curie, PSL university, Paris, France.ORCID 0000-0002-2520-139X
Véronique MosseriDepartment of Biostatistics, Institut Curie, Paris, France.
Daniel PissalouxBiopathology Department, Institut d'Hematologie et d'Oncologie Pediatrique, Centre Léon Bérard, Lyon, France.
Gaelle PierronSomatic Genetic Unit, Institut Curie, Paris, France.
Bernadette BrennanDepartment of Paediatric Oncology, Royal Manchester Children's Hospital, Manchester, UK.
Andrea FerrariPediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.
Frederic ChibonDépartement de Biopathologie, Institut Bergonié, Bordeaux Cedex, France.
Gianni BisognoPediatric Hematology and Oncology Division, Padova University, Padova, Italy.
Gian Luca De SalvoClinical Trials and Biostatistics Unit, IRCCS IstitutoOncologico Veneto, Padova, Italy.
Camille ChakibaDépartement de Biopathologie, Institut Bergonié, Bordeaux Cedex, France.
Nadège CorradiniInstitut d'hématologie et d'Oncologie Pédiatrique, Centre Léon Bérard, Lyon, France.
Véronique Minard-ColinDepartment of Paediatric and Adolescent Oncology, Gustave-Roussy, Villejuif, France.ORCID 0000-0002-0296-5207
Anna KelseyDepartment of Diagnostic Paediatric Histopathology, Royal Manchester Children's Hospital, Manchester, UK.
Dominique Ranchère-VinceBiopathology Department, Institut d'Hematologie et d'Oncologie Pediatrique, Centre Léon Bérard, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A genomic index (GI) tool using array comparative genomic hybridization (aCGH) on tumor cells has emerged as independent prognostic factor associated with the risk of metastatic relapse in synovial sarcoma (SS). The aim was to assess GI in pediatric patients with SS, to determine its value as a prognostic factor. All pediatric/adolescent/young adults' (<25 years) with localized SS prospectively included in the European EpSSG-NRSTS05 protocol with a contributive aCGH were selected. Definition of GI was A

Indexed as

Genetic VariationGenomicsAdolescentAdultAge FactorsChildChild, PreschoolComparative Genomic HybridizationEuropeFemaleHumansMaleNeoplasm GradingNeoplasm MetastasisNeoplasm StagingSarcoma, SynovialAdolescentcomparative genomic hybridizationEpSSGgenomic indexsynovial sarcoma

Identifiers

PMID29533008
PMCPMC5911585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.