ReviewNature reviews. Urology2018
Sexual dysfunction and male infertility.
Review in Nature reviews. Urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
149 citing papers in PubMed, 6 syntheses or guidelines pooled it, 352 citations in OpenAlex.
- The role of the radiologist in the evaluation of male infertility: recommendations of the European Society of Urogenital Radiology-Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for scrotal imaging.European radiology · 2025Guideline
- AI Tools for Assessing Human Fertility Using Risk Factors: A State-of-the-Art Review.Journal of medical systems · 2023Pooled it
- Management of premature ejaculation: a clinical guideline from the Italian Society of Andrology and Sexual Medicine (SIAMS).Journal of endocrinological investigation · 2021Guideline
- Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.Journal of ultrasound · 2020Pooled it
- Psychological aspects of infertility. A systematic review.The Journal of international medical research · 2020Pooled it
- Relationship between cadmium content in semen and male infertility: a meta-analysis.Environmental science and pollution research international · 2019Pooled it
- Efficacy of levocarnitine combined with tadalafil in treating oligozoospermia and asthenozoospermia: effects on serum sex hormones and sexual function.Hormones (Athens, Greece) · 2025Trial
- Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Patient and Partner Sexual Concerns During the First Year After an Implantable Cardioverter Defibrillator: A Secondary Analysis of the P+P Randomized Clinical Trial.The journal of sexual medicine · 2020Trial
- Direct and Gradual Electrical Testicular Shocks Stimulate Spermatogenesis and Activate Sperms in Infertile Men: A Randomized Controlled Trial.American journal of men's healthTrial
- Article
- The role of iron in normal and impaired testicular function.Andrology · 2026Review
- Global research trends in sexual function outcomes after robot-assisted radical prostatectomy: a bibliometric and visualization study.Journal of robotic surgery · 2026Article
- Age Disparity in Couples Seeking First Medical Help for Infertility Has Changed Over the Last Twenty Years: A Socio-Demographic Analysis.The world journal of men's health · 2026Article
- Establishing reference values and evaluating diagnostic utility of scrotal ultrasound for azoospermia subtypes: A cross-sectional study in Guangdong, China.The ultrasound journal · 2026Article
- Multi-omic screening identifies RBMXL3 as a primate-specific RNA-binding protein and candidate regulator of RNA metabolism in human spermatogenesis.Cellular & molecular biology letters · 2026Article
- Effects of quercetin in male rats' testis after consumption of permethrin: a transmission electron microscopy (TEM) study.Scientific reports · 2026Article
- Prevalence of sexual dysfunction and its association with fertility quality of life among infertile men in Henan, China.Reproduction & fertility · 2026Article
- Hormonal crossroads of the heart: from classic endocrine regulation to cardiac hormone secretion: an updated review.Journal of endocrinological investigation · 2026Review
- Mapping the Scientometric Landscape of Andrology: Trends, Gaps, and Future Directions in Male Reproductive Health: A Scoping Review.The world journal of men's health · 2026Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infertility affects up to 12% of all men, and sexual dysfunction occurs frequently in men of reproductive age, causing infertility in some instances. In infertile men, hypoactive sexual desire and lack of sexual satisfaction are the most prevalent types of sexual dysfunction, ranging from 8.9% to 68.7%. Erectile dysfunction and/or premature ejaculation, evaluated with validated tools, have a prevalence of one in six infertile men, and orgasmic dysfunction has a prevalence of one in ten infertile men. In addition, infertile men can experience a heavy psychological burden. Infertility and its associated psychological concerns can underlie sexual dysfunction. Furthermore, general health perturbations can lead to male infertility and/or sexual dysfunction. Erectile dysfunction and male infertility are considered proxies for general health, the former underlying cardiovascular disorders and the latter cancerous and noncancerous conditions. The concept that erectile dysfunction in infertile men might be an early marker of poor general health is emerging. Finally, medications used for general health problems can cause sperm abnormalities and sexual dysfunction. The treatment of some causes of male infertility might improve semen quality and reverse infertility-related sexual dysfunction. In infertile men, an investigation of sexual, general, and psychological health status is advisable to improve reproductive problems and general health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.