Evidence map›Paper›PMID 29532714›Full record

ReviewVirulence2019

Turning on virulence: Mechanisms that underpin the morphologic transition and pathogenicity of

Joseph A McBride, Gregory M Gauthier, Bruce S Klein

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A comprehensive review of neurotropic fungal infections: clinical manifestations and vaccines.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  5. Review
  6. Article
  7. Autochthonous Blastomyces dermatitidis, India.Emerging infectious diseases · 2024
    Article
  8. Article
  9. Review
  10. Benzyl isothiocyanate improves the prognosis ofFrontiers in microbiology · 2023
    Article
  11. Blastomycosis-Some Progress but Still Much to Learn.Journal of fungi (Basel, Switzerland) · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Diagnosis of Pulmonary Infections Due to Endemic Fungi.Diagnostics (Basel, Switzerland) · 2021
    Review
  16. Cryptococcus neoformans: Sex, morphogenesis, and virulence.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Review
  17. Review
  18. Review
  19. Article
  20. Life Cycle ofAnnual review of microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joseph A McBrideDivision of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health , 600 Highland Avenue, Madison , WI , USA.
Gregory M GauthierDivision of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health , 600 Highland Avenue, Madison , WI , USA.
Bruce S KleinDivision of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health , 600 Highland Avenue, Madison , WI , USA.
University of Wisconsin–Madison · US

Funding

PROTECTIVE IMMUNE RESPONSES TO BLASTOMYCES DERMATITIDISR01AI040996 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN, WUETHRICH, MARCEL · 1997 to 2023
$10.4M
Molecular Pathogenesis of BlastomycosisR37AI035681 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BRUCE Steven KLEIN · 2004 to 2026
$6.9M
Microbial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5M
Regulation of vaccine-induced anti-fungal Th17 cellsR01AI093553 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WUETHRICH, MARCEL · 2011 to 2020
$4.5M
MOLECULAR PATHOGENESIS OF BLASTOMYCOSISR01AI035681 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 1995 to 2019
$3.9M
Hybrid histidine kinase: a drug target and path to anti-fungal drug developmentR21AI123758 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2017 to 2018
$408k
NIAID NIH HHS R01 AI035681NIAID NIH HHS R01 AI040996NIAID NIH HHS R01 AI093553NIAID NIH HHS R21 AI123758NIAID NIH HHS R37 AI035681NIAID NIH HHS T32 AI055397
6 · The paper itself

Abstract

This review article focuses on the mechanisms underlying temperature adaptation and virulence of the etiologic agents of blastomycosis,

Indexed as

TemperatureVirulenceAdaptation, PhysiologicalAnimalsBlastomycesBlastomycosisFungal ProteinsHumansHyphaeMiceTranscriptional ActivationVirulence FactorsFungal ProteinsVirulence FactorsBAD1BlastomycosisDPPIVADRK1phase transitionSREBthermal dimorphism

Identifiers

PMID29532714
PMCPMC6779398
OpenAlexW2792754106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.