Evidence map›Paper›PMID 29532242›Full record

ArticleEuropean radiology2018

Vertebral metastases from neuroendocrine tumours: How to avoid false positives on

Mathieu Gauthé, Nathalie Testart Dardel, Fernando Ruiz Santiago, Jessica Ohnona, Valérie Nataf, Françoise Montravers, Jean-Noël Talbot

Abstract read
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. False Positive Findings ofMolecular imaging and radionuclide therapy · 2025
    Article
  4. Review
  5. Detection of Bone Metastases byContrast media & molecular imaging · 2022
    Article
  6. Neuroendocrine neoplasia and bone (Review).Experimental and therapeutic medicine · 2021
    Review
  7. Article
  8. False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma.Nuclear medicine and molecular imaging · 2021
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mathieu GauthéMédecine Nucléaire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France. mathieugauthe@yahoo.fr.
Nathalie Testart DardelNuclear Medicine, CHU de Granada, Granada, Spain.
Fernando Ruiz SantiagoRadiology Department, CHU de Granada, Granada, Spain.
Jessica OhnonaMédecine Nucléaire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France.
Valérie NatafMédecine Nucléaire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France.
Françoise MontraversMédecine Nucléaire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France.
Jean-Noël TalbotMédecine Nucléaire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France.
Physique des Cellules et Cancers · FRSorbonne Université · FRUniversidad de Granada · ESHôpital Tenon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo develop criteria to improve discrimination between vertebral metastases from neuroendocrine tumours (NETs) and benign bone lesions on PET combined with CT using DOTA-D-Phe

methodsIn 535 NET patients,

resultsIn 79 patients (14.8 %), we found 107 metastases, 34 VHs and 31 other benign lesions in the spine. The optimal cut-off values to differentiate metastases from benign lesions were BV ≥0.72 cm

conclusionsThe high sensitivity of KEY POINTS: • Bone metastases in neuroendocrine tumours correlate with prognosis. • Benign bone lesions may mimic metastases on

Indexed as

AdolescentAdultFemaleGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansMaleMiddle AgedNeuroendocrine TumorsOctreotidePositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesSensitivity and SpecificitySpinal NeoplasmsYoung AdultDOTA-Tyr(1)-octreotateGallium RadioisotopesHeterocyclic Compounds, 1-RingOctreotideHaemangiomaIncidental findingsNeuroendocrine tumoursPET/CTSpinal neoplasms

Identifiers

PMID29532242
OpenAlexW2791651406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.