ArticleSurgical endoscopy2018
Diagnostic and therapeutic single-operator cholangiopancreatoscopy with SpyGlassDS™: results of a multicenter retrospective cohort study.
Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07064447 (National Prospective Registry of Direct Cholangiopancreatoscopy by Single Operator), which is not on this map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
National Prospective Registry of Direct Cholangiopancreatoscopy by Single Operator
Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- FIRST BRAZILIAN CONSENSUS ON CHOLANGIOPANCREATOSCOPY BY THE BRAZILIAN SOCIETY OF DIGESTIVE ENDOSCOPY (SOBED).Arquivos de gastroenterologia · 2026Guideline
- Clinical Practice Guidelines for Peroral Cholangioscopy.Journal of hepato-biliary-pancreatic sciences · 2026Guideline
- Efficacy of digital single-operator cholangioscopy in the visual interpretation of indeterminate biliary strictures: a systematic review and meta-analysis.Surgical endoscopy · 2020Pooled it
- Cholangioscopy-guided lithotripsy vs. conventional therapy for complex bile duct stones: a systematic review and meta-analysis.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2020Pooled it
- Inflammatory Fibroid Polyp of the Intrahepatic Biliary Tract: First Documented Case and Diagnostic Relevance of SpyGlass DS Cholangioscopy.Zeitschrift fur Gastroenterologie · 2026Article
- Diagnostic value of peroral choledochoscopy combined with modified biopsy forceps for malignant biliary strictures: a two-center retrospective study.Surgical endoscopy · 2026Article
- Infectious Complications and Safety Outcomes in Cholangioscopy: A Systematic Review and Meta-Analysis.Endoscopy international open · 2026Review
- Prevention of Bacterial Infection in Biliary and Pancreatic Endoscopy-A Review.Diagnostics (Basel, Switzerland) · 2024Review
- Feasibility of Peroral Cholangioscopy in the Initial Endoscopic Retrograde Cholangiopancreatography for Malignant Biliary Strictures.Diagnostics (Basel, Switzerland) · 2024Article
- Endoscopic Management of Difficult Biliary Stones: An Evergreen Issue.Medicina (Kaunas, Lithuania) · 2024Review
- Feasibility, safety and efficacy of endoscopic single-operator cholangioscopy: a retrospective single-center study.Therapeutic advances in gastroenterology · 2024Article
- Antibiotic prophylaxis and post-procedure infectious complications in endoscopic retrograde cholangiopancreatography with peroral cholangioscopy.Endoscopy international open · 2023Article
- Percutaneous transhepatic cholangioscopy for benign and malignant biliary disease using a novel short single-operator cholangioscope.Surgical endoscopy · 2023Observational
- Clinical approach to indeterminate biliary strictures: Clinical presentation, diagnosis, and workup.World journal of gastroenterology · 2023Review
- Mirizzi Syndrome Type IV Successfully Treated with Peroral Single-operator Cholangioscopy-guided Electrohydraulic Lithotripsy: A Case Report with Literature Review.Internal medicine (Tokyo, Japan) · 2022Review
- [Single-operator Cholangioscopy Guided Lithotripsy].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Review
- An international experience with single-operator cholangiopancreatoscopy in patients with altered anatomy.Endoscopy international open · 2022Article
- Advanced Imaging of the Biliary System and Pancreas.Digestive diseases and sciences · 2022Review
- Digital Cholangioscopic Interpretation: When North Meets the South.Digestive diseases and sciences · 2022Observational
- A case of successful removal of a migrated fish bone in the bile duct after pancreaticoduodenectomy using overtube-assisted cholangioscopy.Clinical journal of gastroenterology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe aim of the study was to evaluate the usefulness and diagnostic and therapeutic outcome of the single-operator cholangiopancreatoscopy (SOC) with SpyGlassDS™.
methodsIn a retrospective multicenter study between November 2015 and January 2017, SpyGlassDS™ procedures were analyzed in participating centers. Indications, accuracy of SOC-guided biopsies, management of large bile duct stones, and complications were analyzed. Follow-up was 4 months.
resultsTwo hundred and six patients out of 250 examinations were evaluated. Indications were biliary stones (n = 132), bile duct stenosis (n = 93), stones and stenosis combined (n = 24), and bile duct leakage (n = 1). Of the 117 cases which were suspicious of malignancy, in 99 cases the lesion could be stratified into benign (n = 55) or malignant (n = 44) indicating a sensitivity of 95.5% and a specificity of 94.5% for the indication tumor. SOC-guided biopsies revealed a sensitivity of 57.7% with a specificity of 100%. In 107 examinations, biliary stones were visualized and could be completely removed in 91.1% with a need of three procedures (range 1-6) to achieve final stone clearance. In 75 cases, lithotripsy was performed and was successful in 71 cases (95%). Four out of 45 patients (8.9%) underwent cholecystectomy with surgical bile duct revision as a final therapy. Adverse Event (AE) occurred in 33/250 patients (13.2%) and Serious Adverse Event (SAE) occurred in 1/250 patients (0.4%). Cholangitis was 1% (n = 102) after peri-interventional administration of antibiotics and 12.8% (n = 148) without antibiotic prophylaxis (p < 0.001).
conclusionsSOC with SpyGlassDS™ became a new standard for the diagnosis of indefinite biliary lesions and therapy of large bile duct stones. The diagnostic yield of SOC-guided biopsies facilitated a definite diagnosis in most cases and should be improved by standardized biopsy protocols. SOC-guided interventions allowed removal of large biliary stones by SOC-guided lithotripsy. The complication rate of 13.2% can be considerably reduced by use of a single-shot antibiotic treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.