ArticleJournal of behavioral medicine2018
Temporal relationship between daily pain and actigraphy sleep patterns in pediatric sickle cell disease.
Article in Journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387758 (Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review: Pain and Emotional Functioning in Pediatric Sickle Cell Disease.Journal of clinical psychology in medical settings · 2020Pooled it
- Feasibility and preliminary efficacy of the Balance Program to reduce pain-related disability in pediatric sickle cell disease.Pediatric blood & cancer · 2023Trial
- The relation between sleep and pain sensitization in pediatric sickle cell disease.Journal of pediatric psychology · 2026Article
- Recommended measurement protocols for sickle cell disease in the PhenX toolkit: psychosocial factors and social determinants of health.Journal of sickle cell disease · 2025Article
- Pain, sleep, fatigue, and health-related quality of life in pediatric sickle cell disease: a serial multiple mediator analysis.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Sleep Behaviour in Sickle Cell Disease: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2024Review
- Sleep and fatigue among youth with sickle cell disease: A daily diary study.Journal of behavioral medicine · 2023Article
- The relationship between pain and sleep in pediatric sickle cell disease.Pediatric blood & cancer · 2023Article
- The complexities of the sleep-pain relationship in adolescents: A critical review.Sleep medicine reviews · 2023Review
- Use of consumer wearables to monitor and predict pain in patients with sickle cell disease.Frontiers in digital health · 2023Article
- Sleep quality and pain in adolescents and young adults with sickle cell disease.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Data visualization as an intervention for pediatric chronic pain: a pilot feasibility study protocol for a randomized controlled crossover trial.Pilot and feasibility studies · 2022Article
- Identifying Chronic Pain Subgroups in Pediatric Sickle Cell Disease: A Cluster-Analytic Approach.The Clinical journal of pain · 2022Article
- Pediatric sleep and pain: etiologies, consequences, and clinical considerations.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Review
- Correlation Between Pre-Operative Sleep Disturbance and Post-Operative Pain in Patients With Rotator Cuff Tear.Frontiers in integrative neuroscience · 2022Article
- Pediatric sickle cell pain-sleep relationships: The roles of positive and negative affect.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Article
- Pediatric recurring pain in the community: the role of children's sleep and internalizing symptoms.Journal of behavioral medicine · 2021Article
- Identifying elevated risk for future pain crises in sickle-cell disease using photoplethysmogram patterns measured during sleep: A machine learning approach.Frontiers in digital health · 2021Article
- Sleep Deficiency and Pediatric Chronic Pain.The Nursing clinics of North America · 2021Review
- Sleep disturbance in adults with sickle cell disease: relationships with executive and psychological functioning.Annals of hematology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limited research is available on the relationship between objective sleep patterns and pain in children with SCD. Research in other chronic pain populations suggests that the effect of sleep disruption on pain may be stronger than the effect of pain on sleep that night. To examine the bi-directional relationship between objective sleep patterns and daily pain in a pediatric SCD sample. Participants were 30 African American children with SCD 8-18 years (13 ± 2.8 years; 66.7% female) with frequent pain. Children and parents completed questionnaires to assess pain, medications, and depression/anxiety. Over a 14-day period, children completed a pain diary and ambulatory actigraphy monitoring to assess nighttime sleep (duration, efficiency and WASO). Greater pain severity was associated with worse sleep efficiency and greater WASO that night, controlling for age, sex, opioid medication, and depression/anxiety symptoms. Worse sleep efficiency was associated with the occurrence of pain and more severe pain the next day. There was no relationship between WASO and pain. Similarly, sleep duration did not influence pain. Results lend support for a bi-directional relationship between sleep parameters and daily pain in pediatric SCD, and identify sleep as a potential target for future research and intervention.
Indexed as
Identifiers
29532199What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.