Evidence map›Paper›PMID 29532143›Full record

ArticleWorld journal of surgery2018

Primary Hyperparathyroidism is Underdiagnosed and Suboptimally Treated in the Clinical Setting.

Jacob Enell, Haytham Bayadsi, Ewa Lundgren, Joakim Hennings

Abstract read
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Article in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jacob EnellDepartment of Surgical and Perioperative Sciences, Umeå University, 901 85, Umeå, Sweden.
Haytham BayadsiDepartment of Surgical and Perioperative Sciences, Umeå University, 901 85, Umeå, Sweden.
Ewa LundgrenDepartment of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.
Joakim HenningsDepartment of Surgical and Perioperative Sciences, Umeå University, 901 85, Umeå, Sweden. joakim.hennings@umu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate whether patients presenting with laboratory results consistent with primary hyperparathyroidism (pHPT) are managed in accordance with guidelines.

methodsThe laboratory database at a hospital in Sweden, serving 127,000 inhabitants, was searched for patients with biochemically determined pHPT. During 2014, a total of 365 patients with biochemical laboratory tests consistent with pHPT were identified. Patients with possible differential diagnoses or other reasons for not being investigated according to international guidelines were excluded after scrutinizing records, after new blood tests, and clinical assessments by endocrine surgeons.

resultsAltogether, 92 patients had been referred to specialists and 82 had not. The latter group had lower serum calcium (median 2.54 mmol/L) and PTH (5.7 pmol/L). Out of these 82 cases, 9 patients were diagnosed with pHPT or had some sort of long-term follow-up planned as outpatients.

conclusionPrimary hyperparathyroidism is overlooked and underdiagnosed in a number of patients in the clinical setting. It is important to provide local guidelines for the management of patients presenting with mild pHPT to ensure that these patients receive proper evaluation and follow-up according to current research.

Indexed as

AdolescentAdultAgedAged, 80 and overCalciumDiagnostic ErrorsFemaleGuideline AdherenceHumansHyperparathyroidism, PrimaryMaleMiddle AgedParathyroid HormonePractice Guidelines as TopicReferral and ConsultationSwedenCalciumParathyroid Hormone

Identifiers

PMID29532143
PMCPMC6097779

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.