ReviewACS central science2018
Walking Metals for Remote Functionalization.
Review in ACS central science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed.
- Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki-Hiyama-Kishi Coupling.Angewandte Chemie (International ed. in English) · 2026Article
- Palladium-catalyzed enantioselective alkenylation of acyclic alkenols: Broad scope with alkenyl bromides.Science advances · 2026Article
- Ligand relay catalysis enables asymmetric migratory dearomative annulation of N-heteroarenes.Nature communications · 2026Article
- Nickel/Photoredox Dual-Catalyzed Migratory Reductive C(spAngewandte Chemie (International ed. in English) · 2026Article
- Cation Sampling Enables Regiodivergent Distal Functionalization of Ketones.Journal of the American Chemical Society · 2026Article
- Contra-Thermodynamic Chain-Walking Isomerization: A Sustainable Tool for Selective Molecular Editing in Green Chemistry.ChemSusChem · 2026Article
- Chemo-divergent and regioselective branched cross-hydroalkenylation of electron-deficient olefins and vinylarenes directed by (NHC)Ni(II) catalysts.Nature communications · 2026Article
- Alkyne migratory functionalization via C(spNature communications · 2026Article
- Precise borylation of targeted methyl group via an orderly chain-walking strategy.Science advances · 2026Article
- Stereodivergent synthesis of chiral amines bearing vicinal stereocenters via hydroamination of trisubstituted alkenes.Nature communications · 2026Article
- Boosting the Nucleophilicity of the Diphenylphosphide Anion with Crown Ether Supported Heavy Alkali Metals to Facilitate Highly Efficient Catalytic Alkene Isomerisation.Angewandte Chemie (International ed. in English) · 2026Article
- Stereodivergent construction of non-adjacent stereocentres via migratory functionalization of alkenes.Nature chemistry · 2026Article
- Stereoselective cyano translocation reaction enabled by photoenzymatic catalysis.Nature communications · 2026Article
- Electrochemical reduction of unsaturated carbon-carbon bonds via 3d transition-metal catalysis.Beilstein journal of organic chemistry · 2026Review
- Noncovalent interaction-driven regio- and enantioselective hydroalkynylation of unactivated alkenes to access remote chiral nitriles.Science advances · 2025Article
- Head-tail carboboration of multisubstituted alkenes enabled by chain recognition.Nature chemistry · 2025Article
- Ligand-modulated regiodivergent alkenylboration of allylarenes: Reaction development and mechanistic study.Fundamental research · 2025Article
- Terminal Selective Arylation of Inert Alkanes via Radical-Organometallic Crossover.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- The role of 1,4-palladium migration in C(spRSC advances · 2025Review
- Isocampholenic Acid Derivatives as Potential Fragrances.Molecules (Basel, Switzerland) · 2025Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The distant and selective activation of unreactive C-H and C-C bonds remains one of the biggest challenges in organic chemistry. In recent years, the development of remote functionalization has received growing interest as it allows for the activation of rather challenging C-H and C-C bonds distant from the initiation point by means of a "metal-walk". A "metal-walk" or "chain-walk" is defined by an iterative series of consecutive 1,2- or 1,3-hydride shifts of a metal complex along a single hydrocarbon chain. With this approach, simple building blocks or mixtures thereof can be transformed into complex scaffolds in a convergent and unified strategy. A variety of catalytic systems have been developed and refined over the past decade ranging from late-transition-metal complexes to more sustainable iron- and cobalt-based systems. As the possibilities of this field are slowly unfolding, this area of research will contribute considerably to provide solutions to yet unmet synthetic challenges.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.