Evidence map›Paper›PMID 29532008›Full record

ArticleNPJ breast cancer2018

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

A Mukherjee, R Russell, Suet-Feung Chin, B Liu, O M Rueda, H R Ali, G Turashvili, B Mahler-Araujo, I O Ellis, S Aparicio and 2 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

A Mukherjee *1Department of Histopathology, Division of Cancer and Stem cells, School of Medicine, University of Nottingham, Nottingham, UK.
R Russell3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Suet-Feung Chin3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.ORCID 0000-0001-5697-1082
B Liu3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
O M Rueda3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
H R Ali3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
G Turashvili5Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC Canada.
B Mahler-Araujo6Addenbrooke's Hospital, Cambridge Breast Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
I O Ellis1Department of Histopathology, Division of Cancer and Stem cells, School of Medicine, University of Nottingham, Nottingham, UK.
S Aparicio5Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC Canada.
C Caldas3CRUK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
E Provenzano *6Addenbrooke's Hospital, Cambridge Breast Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
University of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GBNottingham University Hospitals NHS Trust · GBUniversity of British Columbia · CA

Funding

Cancer Research UK 16942Cancer Research UK 25815
6 · The paper itself

Abstract

The integration of genomic and transcriptomic profiles of 2000 breast tumours from the METABRIC [Molecular Taxonomy of Breast Cancer International Consortium] cohort revealed ten subtypes, termed integrative clusters (IntClust/s), characterised by distinct genomic drivers. Central histopathology (

Identifiers

PMID29532008
PMCPMC5841292
OpenAlexW2793956875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.