Evidence map›Paper›PMID 29531967›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2018

Radiomic signature of infiltration in peritumoral edema predicts subsequent recurrence in glioblastoma: implications for personalized radiotherapy planning.

Saima Rathore, Hamed Akbari, Jimit Doshi, Gaurav Shukla, Martin Rozycki, Michel Bilello, Robert Lustig, Christos Davatzikos

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Artificial intelligence in neuro-oncology: methodological bases, practical applications and ethical and regulatory issues.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  9. Fusion of habitat analysis and deep learning on contrast-enhanced T1-weighted imaging for predicting Ki-67 status in pediatric brain tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Deep learning for autosegmentation for radiotherapy treatment planning: State-of-the-art and novel perspectives.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Review
  14. Article
  15. Knowledge-Informed Machine Learning for Cancer Diagnosis and Prognosis: A Review.IEEE transactions on automation science and engineering : a publication of the IEEE Robotics and Automation Society · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Saima RathoreUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Hamed AkbariUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Jimit DoshiUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Gaurav ShuklaUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Martin RozyckiUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Michel BilelloUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Robert LustigUniversity of Pennsylvania, Department of Radiation Oncology, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
Christos DavatzikosUniversity of Pennsylvania, Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, Philadelphia, Pennsylvania, United States.
University of Pennsylvania · USUniversity of Pennsylvania Health System · US

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
NCI NIH HHS U24 CA189523NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Standard surgical resection of glioblastoma, mainly guided by the enhancement on postcontrast T1-weighted magnetic resonance imaging (MRI), disregards infiltrating tumor within the peritumoral edema region (ED). Subsequent radiotherapy typically delivers uniform radiation to peritumoral FLAIR-hyperintense regions, without attempting to target areas likely to be infiltrated more heavily. Noninvasive

Indexed as

glioblastomamachine learningradiomicstumor infiltrationtumor recurrence

Identifiers

PMID29531967
PMCPMC5831697
OpenAlexW2790497327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.