Evidence map›Paper›PMID 29531964›Full record

ArticleNeurophotonics2018

Overexpression of channelrhodopsin-2 interferes with the GABAb receptor-mediated depression of GABA release from the somatostatin-containing interneurons of the prefrontal cortex.

Lei Liu, Wataru Ito, Alexei Morozov

Open access · bronzeAbstract read
In one paragraph

Article in Neurophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Dendrite-Targeting Inhibitory Interneurons Form Biased Circuits with Deep and Superficial Pyramidal Cells in Hippocampal CA1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. Article
  4. Presynaptic GABAeLife · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lei LiuVirginia Tech Carilion Research Institute, Roanoke, Virginia, United States.
Wataru ItoVirginia Tech Carilion Research Institute, Roanoke, Virginia, United States.
Alexei MorozovVirginia Tech Carilion Research Institute, Roanoke, Virginia, United States.ORCID https://orcid.org/0000-0003-0495-3987
Carilion Clinic · USVirginia Tech · US

Funding

Reorganization of PFC inhibitory network by observational fearR21MH112093 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MOROZOV, ALEXEI · 2016 to 2017
$443k
NIMH NIH HHS R21 MH112093
6 · The paper itself

Abstract

Region and cell-type restricted expression of light-activated ion channels is the indispensable tool to study properties of synapses in specific circuits and to monitor synaptic alterations by various stimuli including neuromodulators and behaviors, both

Indexed as

artifactchannelrhodopsin 2GABAb receptorpresynaptic releasesomatostatin interneurons

Identifiers

PMID29531964
PMCPMC5831728
OpenAlexW2951386617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.