Evidence map›Paper›PMID 29531962›Full record

ArticleNeurophotonics2018

Noninvasive detection of acute cerebral hypoxia and subsequent matrix-metalloproteinase activity in a mouse model of cerebral ischemia using multispectral-optoacoustic-tomography.

Ruiqing Ni, Markus Vaas, Wuwei Ren, Jan Klohs

Open access · bronzeAbstract read
In one paragraph

Article in Neurophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  5. Article
  6. Non-Invasive Photoacoustic Cerebrovascular Monitoring of Early-Stage Ischemic Strokes In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Article
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  14. Review
  15. Multi-scale optoacoustic molecular imaging of brain diseases.European journal of nuclear medicine and molecular imaging · 2021
    Review
  16. Photoacoustics · 2021
    Article
  17. Review
  18. Review
  19. Multimodal Contrast Agents for Optoacoustic Brain Imaging in Small Animals.Frontiers in bioengineering and biotechnology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ruiqing NiUniversity of Zurich and ETH Zurich, Institute for Biomedical Engineering, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-0793-2113
Markus VaasUniversity of Zurich and ETH Zurich, Institute for Biomedical Engineering, Zurich, Switzerland.
Wuwei RenUniversity of Zurich and ETH Zurich, Institute for Biomedical Engineering, Zurich, Switzerland.
Jan KlohsUniversity of Zurich and ETH Zurich, Institute for Biomedical Engineering, Zurich, Switzerland.
ETH Zurich · CHInstitute for Biomedical Engineering · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen metabolism and matrix metalloproteinases (MMPs) play important roles in the pathophysiology of cerebral ischemia. Using multispectral optoacoustic tomography (MSOT) imaging, we visualized

Indexed as

animal modelcerebral ischemiahemodynamicsmagnetic resonance imagingmatrix metalloproteinasesmultispectral optoacoustic imaging

Identifiers

PMID29531962
PMCPMC5829216
OpenAlexW2791004583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.