Evidence map›Paper›PMID 29531919›Full record

ArticleAdvanced biomedical research2018

Maryam Golshani, Melina Ghasemian, Nematollah Gheibi, Saeid Bouzari

Open access · goldAbstract read
In one paragraph

Article in Advanced biomedical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maryam GolshaniDepartment of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran.
Melina GhasemianDepartment of Biotechemistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Nematollah GheibiDepartment of Biotechemistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Saeid BouzariDepartment of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran.
Pasteur Institute of Iran · IRQazvin University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundL7/L12 is a protective antigen conserved in main MATERIALS AND

methodsThe purpose of the current study was to

resultsAnalysis and validation of the fusion proteins three-dimensional models showed that both models are in the range of native proteins. However, L7/L12-SOmp2b structure was more valid than the SOmp2b-L7/L12 model and subjected to

conclusionsOur data indicates that L7/L12-SOmp2b fusion protein has a potential to induce both B- and T-cell-mediated immune responses and it can be evaluated as a new subunit vaccine candidate against brucellosis.

Indexed as

Brucellacloningfusion proteinin silico designL7/L12outer membrane protein 2b

Identifiers

PMID29531919
PMCPMC5840964
OpenAlexW2792309473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.