Evidence map›Paper›PMID 29531480›Full record

ArticleClinical medicine insights. Ear, nose and throat2018

Prognostic Value and Changes of Auditory Brain Stem Response in Children With Bacterial Meningitis in Luanda, Angola.

Mariia Karppinen, Atte Sjövall, Tuula Pelkonen, Luis Bernardino, Irmeli Roine, Anne Pitkäranta, Antti A Aarnisalo, Päivi Nevalainen, Leena Lauronen

Open access · diamondAbstract read
In one paragraph

Article in Clinical medicine insights. Ear, nose and throat, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mariia KarppinenChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Atte SjövallFaculty of Medicine, University of Helsinki, Helsinki, Finland.
Tuula PelkonenChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Luis BernardinoDavid Bernardino Children's Hospital, Luanda, Angola.
Irmeli RoineFaculty of Medicine, University Diego Portales, Santiago, Chile.
Anne PitkärantaFaculty of Medicine, University of Helsinki, Helsinki, Finland.
Antti A AarnisaloFaculty of Medicine, University of Helsinki, Helsinki, Finland.
Päivi NevalainenChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Leena LauronenChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
University of Helsinki · FIHelsinki Children's Hospital · FIHelsinki University Hospital · FIDiego Portales University · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the role of single and repeated auditory brain stem response (ABR) in predicting mortality and severe neurological injury among children having bacterial meningitis (BM) in Luanda, Angola.

methodsThe morphology of ABR traces of 221 children (aged 2 months to 12 years) from admission day was analyzed and compared with age-matched normative data. Absence and delay of traces were compared with mortality and mortality or severe neurological injury in subgroup analyses. Outcome was also evaluated with repeated ABR of 166 children based on presence or absence of responses at 80 dB nHL (normal hearing level) stimulation level.

resultsIndividually, the absence of typical ABR waveform did not signify poor outcome. At the group level, latencies and interpeak latencies (IPLs) were significantly prolonged among patients with BM in comparison with controls, and the prolongation correlated with higher mortality or severe neurological sequelae.

conclusionsWe confirmed the effect of BM on neural conduction time in auditory pathway. However, ABR in similar settings seems not useful for individual prognostication, although at the group level, delayed latencies, IPLs, or both associated with poorer outcome.

Indexed as

Auditory brain stem responsechildhood bacterial meningitisdeveloping countryprognosis

Identifiers

PMID29531480
PMCPMC5843090
OpenAlexW2792467031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.