Evidence map›Paper›PMID 29531453›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018

Extracorporeal Membrane Oxygenation in Drug Overdose: A Clinical Case Series.

C Vignesh, Madhan Kumar, Ramesh Venkataraman, Senthilkumar Rajagopal, Nagarajan Ramakrishnan, Babu K Abraham

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Lipid emulsion for xenobiotic overdose: PRO.British journal of clinical pharmacology · 2023
    Article
  5. The Role of Angiotensin II in Poisoning-Induced Shock-a Review.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Severe Amlodipine Toxicity: A Case Rescued with Extracorporeal Membrane Oxygenation.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C VigneshDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Madhan KumarDepartment of Cardiothoracic surgery, Mechanical Circulatory Support and Transplantation, Apollo Hospitals, Chennai, Tamil Nadu, India.
Ramesh VenkataramanDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Senthilkumar RajagopalDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Nagarajan RamakrishnanDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Babu K AbrahamDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overdose of cardiovascular medications such as beta blockers and calcium channel blockers cause impaired cardiac contractility, vasoplegia, and/or rhythm disturbances. In addition to conventional management of limiting absorption, increasing elimination and hemodynamic support intravenous (IV) calcium infusion, hyperinsulinemia-euglycemia therapy, glucagon infusion, and IV lipid emulsion have been tried. Extracorporeal circulatory assist device support has been reported as a rescue therapy in overdose refractory to maximal medical therapy. We report three patients with cardiovascular medication overdose presenting with profound cardiovascular instability refractory to medical therapy. Venoarterial extracorporeal membrane oxygenation support (VA ECMO) was initiated to provide hemodynamic support. Despite the occurrence of device-associated complications, the outcome was good and all patients survived. VA ECMO may be considered in patients with severe refractory shock due to cardiotoxic medication overdose.

Indexed as

Beta blockerscalcium channel blockerscirculatory assist devicedrug overdoseextracorporeal membrane oxygenation

Identifiers

PMID29531453
PMCPMC5842452
OpenAlexW2794221574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.