ArticleScientific reports2018
Electrochemical Evaluations of Fractal Microelectrodes for Energy Efficient Neurostimulation.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 51 citations in OpenAlex.
- Integrated hierarchical surface restructuring of assembled electrode arrays for next-generation neural interfaces.PloS one · 2026Article
- Electrical Stimulation of Cells: Drivers, Technology, and Effects.Chemical reviews · 2025Review
- Softening, Conformable, and Stretchable Conductors for Implantable Bioelectronics Interfaces.Advanced materials technologies · 2025Article
- A flexible, thin-film microchannel electrode array device for selective subdiaphragmatic vagus nerve recording.Microsystems & nanoengineering · 2024Article
- Fractal Microelectrodes for More Energy-Efficient Cervical Vagus Nerve Stimulation.Advanced healthcare materials · 2023Article
- In Vivo Penetrating Microelectrodes for Brain Electrophysiology.Sensors (Basel, Switzerland) · 2022Review
- Recent Advances in Cochlear Implant Electrode Array Design Parameters.Micromachines · 2022Review
- Histological and electrophysiological evidence on the safe operation of a sharp-tip multimodal optrode during infrared neuromodulation of the rat cortex.Scientific reports · 2022Article
- Imaging the Efficiency of Poly(3,4-ethylenedioxythiophene) Doped with Acid-Functionalized Carbon Nanotube and Iridium Oxide Electrode Coatings for Microstimulation.Advanced nanobiomed research · 2021Article
- Nano-optoelectrodes Integrated with Flexible Multifunctional Fiber Probes by High-Throughput Scalable Fabrication.ACS applied materials & interfaces · 2021Article
- The Role of Electrode-Site Placement in the Long-Term Stability of Intracortical Microstimulation.Frontiers in neuroscience · 2021Article
- Novel Electrode Designs for Neurostimulation in Regenerative Medicine: Activation of Stem Cells.Bioelectricity · 2020Review
- Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves.Communications biology · 2020Article
- Sputtered porous Pt for wafer-scale manufacture of low-impedance flexible microelectrodes.Journal of neural engineering · 2020Article
- In Vitro/Ex Vivo Investigation of Modified Utah Electrode Array to Selectively Sense and Pace the Sub-Surface Cardiac His Bundle.ACS biomaterials science & engineering · 2020Article
- Neuroadhesive protein coating improves the chronic performance of neuroelectronics in mouse brain.Biosensors & bioelectronics · 2020Article
- Application of a Novel Measurement Setup for Characterization of Graphene Microelectrodes and a Comparative Study of Variables Influencing Charge Injection Limits of Implantable Microelectrodes.Sensors (Basel, Switzerland) · 2019Article
- Effect of Electrode Shape and Flow Conditions on the Electrochemical Detection with Band Microelectrodes.Sensors (Basel, Switzerland) · 2018Article
- Modeling the Improved Visual Acuity Using Photodiode Based Retinal Implants Featuring Fractal Electrodes.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advancements in microfabrication has enabled manufacturing of microscopic neurostimulation electrodes with smaller footprint than ever possible. The smaller electrodes can potentially reduce tissue damage and allow better spatial resolution for neural stimulation. Although electrodes of any shape can easily be fabricated, substantial effort have been focused on identification and characterization of new materials and surface morphology for efficient charge injection, while maintaining simple circular or rectangular Euclidean electrode geometries. In this work we provide a systematic electrochemical evaluation of charge injection capacities of serpentine and fractal-shaped platinum microelectrodes and compare their performance with traditional circular microelectrodes. Our findings indicate that the increase in electrode perimeter leads to an increase in maximum charge injection capacity. Furthermore, we found that the electrode geometry can have even more significant impact on electrode performance than having a larger perimeter for a given surface area. The fractal-shaped microelectrodes, despite having smaller perimeter than other designs, demonstrated superior charge injection capacity. Our results suggest that electrode design can significantly affect both Faradaic and non-Faradaic electrochemical processes, which may be optimized to enable a more energy efficient design for neurostimulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.