Evidence map›Paper›PMID 29531133›Full record

ArticleInfection and immunity2018

Determinants of Raft Partitioning of the Helicobacter pylori Pore-Forming Toxin VacA.

Krishnan Raghunathan, Nora J Foegeding, Anne M Campbell, Timothy L Cover, Melanie D Ohi, Anne K Kenworthy

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Cell lipid biology in infections: an overview.Frontiers in cellular and infection microbiology · 2023
    Review
  6. Challenges and approaches to studying pore-forming proteins.Biochemical Society transactions · 2021
    Review
  7. Article
  8. Article
  9. Helicobacter pylori lipids can form ordered membrane domains (rafts).Biochimica et biophysica acta. Biomembranes · 2019
    Article
  10. Cryo-EM structures ofProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Krishnan Raghunathan *Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-2228-6313
Nora J Foegeding *Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
Anne M CampbellDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Timothy L CoverDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0001-8503-002X
Melanie D OhiLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
Anne K KenworthyDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA anne.kenworthy@vanderbilt.edu.
Vanderbilt University · USUniversity of Michigan · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2009 to 2026
$27.5M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
Type IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7M
Function and assembly of toxin-stabilized domainsR01GM106720 · NIGMS · VANDERBILT UNIVERSITY · PI KENWORTHY, ANNE K · 2013 to 2020
$2.7M
LSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560k
Pathogenesis of Helicobacter pylori infectionI01BX000627 · VA · VETERANS HEALTH ADMINISTRATION · PI COVER, TIMOTHY L · 2011 to 2018
–
BLRD VA I01 BX000627NCI NIH HHS P01 CA116087NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R01 GM106720NIGMS NIH HHS T32 GM008320NIH HHS S10 OD021630
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsBacterial ToxinsHelicobacter pyloriHost-Pathogen InteractionsMembrane MicrodomainsStomach NeoplasmsVacuolesBacterial ProteinsBacterial ToxinsVacA protein, Helicobacter pyloriGPMVHelicobacter pylorilipid raftsoligomerizationordered phasephase separationpore formationpore-forming toxinsVacA

Identifiers

PMID29531133
PMCPMC5913846
OpenAlexW2791264255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.