Evidence map›Paper›PMID 29531132›Full record

ArticleInfection and immunity2018

Serum Amyloid P and IgG Exhibit Differential Capabilities in the Activation of the Innate Immune System in Response to Bacillus anthracis Peptidoglycan.

Alanson W Girton, Narcis I Popescu, Ravi S Keshari, Tarea Burgett, Florea Lupu, K Mark Coggeshall

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Gold micro-particles for knee osteoarthritis.European journal of pain (London, England) · 2022
    Trial
  2. Article
  3. Article
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  6. Article
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  8. Frontiers in immunology · 2020
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alanson W GirtonDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Narcis I PopescuArthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
Ravi S KeshariCardiovascular Biology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
Tarea BurgettArthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
Florea LupuCardiovascular Biology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
K Mark CoggeshallDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Mark-Coggeshall@omrf.org.
Oklahoma Medical Research Foundation · USUniversity of Oklahoma Health Sciences Center · US

Funding

Translation of immunologic technologies from basic research into pre-clinical nonU19AI062629 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI COGGESHALL, KENNETH MARK · 2004 to 2023
$56.2M
Development of a mouse model of peptidoglycan-induced pathologyR21AI113020 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI COGGESHALL, KENNETH MARK, LUPU, FLOREA · 2014 to 2015
$471k
NIAID NIH HHS R21 AI113020NIAID NIH HHS U19 AI062629
6 · The paper itself

Abstract

We showed that human IgG supported the response by human innate immune cells to peptidoglycan (PGN) from

Indexed as

Bacillus anthracisHumansImmunity, InnateImmunoglobulin GPeptidoglycanSerum Amyloid P-ComponentImmunoglobulin GPeptidoglycanSerum Amyloid P-ComponentBacillus anthracishost responseinflammationopsoninpeptidoglycanserum amyloid P

Identifiers

PMID29531132
PMCPMC5913848
OpenAlexW2792460085

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.