Evidence map›Paper›PMID 29531104›Full record

ArticleAnnals of family medicine2018

A Core Outcome Set for Multimorbidity Research (COSmm).

Susan M Smith, Emma Wallace, Chris Salisbury, Maxime Sasseville, Elizabeth Bayliss, Martin Fortin

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of family medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05593835 (Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform), which is not on this map. Cited by 130 papers, 26 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 26 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05593835 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform

TypeinterventionalSponsorUniversidade Nova de LisboaRan2025 to 2027Enrolled1,380ConditionsChronic DiseaseArmsMETHIS Platform, Goal-Oriented Care Training Program
3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 26 syntheses or guidelines pooled it, 228 citations in OpenAlex.

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  14. Influence of health-system change on treatment burden: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Susan M SmithHRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland susansmith@rcsi.ie.
Emma WallaceHRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland.
Chris SalisburyCentre for Academic Primary Care, NIHR School for Primary Care Research, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
Maxime SassevilleDepartment of Health Sciences Research, Research Chair on Chronic Diseases in Primary Care, Chicoutimi (Quebec), Canada.
Elizabeth BaylissInstitute for Health Research, Kaiser Permanente Colorado, University of Colorado School of Medicine, Denver, Colorado.
Martin FortinDépartement de médecine de famille, Université de Sherbrooke, Sherbrooke (Québec), Canada.
Royal College of Surgeons in Ireland · IEKaiser Permanente · USUniversité de Sherbrooke · CAUniversité du Québec à Chicoutimi · CAUniversity of Bristol · GB

Funding

Department of Health 12/130/15
6 · The paper itself

Abstract

purposeWe aimed to develop a consensus-based set of core outcomes specifically for studies in multimorbidity.

methodsWe undertook a consensus study following the COS-STAR (Core Outcome Set-STAndards for Reporting) guidelines for the design and reporting of core outcome sets. A Delphi panel of experts completed a web-based survey with 2 rounds. Panelists were presented with a range of outcomes that had been identified in previous workshops and a related systematic review. They indicated their level of agreement on whether each outcome should be included in the core set using a 5-point Likert scale, and outcomes reaching a prespecified consensus level were included.

resultsOf 30 individuals invited to be panelists, 26 from 13 countries agreed. All 26 completed both rounds of the survey. The Delphi panel reached consensus on 17 outcomes for inclusion in a core outcome set for multimorbidity (COSmm). The highest-ranked outcomes were health-related quality of life, mental health outcomes, and mortality. Other outcomes were grouped into overarching themes of patient-reported impacts and behaviors (treatment burden, self-rated health, self-management behavior, self-efficacy, adherence); physical activity and function (activities of daily living, physical function, physical activity); consultation related (communication, shared decision making, prioritization); and health systems (health care use, costs, quality of health care).

conclusionsThis consensus study involved a wide range of international experts who identified a large number of outcomes for multimorbidity intervention studies. Our results suggest that quality of life, mental health outcomes, and mortality should be regarded as essential core outcomes. Researchers should, however, also consider the full range of outcomes when designing studies to capture important domains in multimorbidity depending on individual study aims and interventions.

Indexed as

MultimorbidityConsensusDelphi TechniqueGuidelines as TopicHumansPatient Reported Outcome MeasuresQuality of LifeResearchSurveys and Questionnaireschronic diseasecomplexitycore outcome setmethodologymultimorbidityprimary careresearch

Identifiers

PMID29531104
PMCPMC5847351
OpenAlexW2789603165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.