Trial reportAnnals of family medicine2018
Treating Subthreshold Depression in Primary Care: A Randomized Controlled Trial of Behavioral Activation With Mindfulness.
Trial report in Annals of family medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Evaluation of a probiotic blend on psychosocial health and biomarkers of inflammatory, immune and stress response in adults with subthreshold depression: a double-blind, randomised, placebo-controlled trial.The British journal of nutrition · 2026Trial
- Effect of AI-Based Natural Language Feedback on Engagement and Clinical Outcomes in Fully Self-Guided Internet-Based Cognitive Behavioral Therapy for Depression: 3-Arm Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Behavioral Activation Therapy for Subthreshold Depression in Stroke Patients: An Exploratory Randomized Controlled Trial.Neuropsychiatric disease and treatment · 2022Trial
- The impact of primary care behavioral health services on patient behaviors: A randomized controlled trial.Families, systems & health : the journal of collaborative family healthcare · 2020Trial
- Efficacy of a video-viewing intervention of smartphone-based positive word stimulation on depressive symptoms in individuals with subthreshold depression: Protocol for a randomized controlled trial.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Effectiveness of a Group Behavioral Activation Intervention for Subthreshold Depression in Chinese University Students: A Randomized Controlled Trial.The Psychiatric quarterly · 2025Article
- Associations among subthreshold depression, cognitive bias, and mentalization in university students.BMC public health · 2025Article
- Exploring patient experiences with a mindfulness course in a general practice setting: a qualitative study.BMC primary care · 2025Article
- Sexual Minority Men Living with HIV's Interest in Yoga vs. MBSR as an Adjunct to an App-Based Positive Affect Intervention: A Focus Group Study.Current research in complementary & alternative medicine · 2025Article
- Chinese Medicine as First-Line Treatment for Subthreshold Mental Disorders in Primary Care: Opportunities and Challenges.F1000Research · 2025Review
- Mind-Body Medicine in the Treatment of Depression: A Narrative Review of Efficacy, Safety and Mechanisms.Current psychiatry reports · 2024Review
- A randomized controlled trial on the effects and acceptability of individual mindfulness techniques - meditation and yoga - on anxiety and depression in people with Parkinson's disease: a study protocol.BMC complementary medicine and therapies · 2023Article
- Subthreshold Depression: A Systematic Review and Network Meta-Analysis of Non-Pharmacological Interventions.Neuropsychiatric disease and treatment · 2023Review
- Preventing the onset of depressive disorders in low-and middle-income countries: An overview.Global mental health (Cambridge, England) · 2023Review
- A Brief Mindfulness-Based Cognitive Therapy (MBCT) Intervention as a Population-Level Strategy for Anxiety and Depression.International journal of cognitive therapy · 2021Article
- Comparative Efficacy of Multiple Therapies for the Treatment of Patients With Subthreshold Depression: A Systematic Review and Network Meta-Analysis.Frontiers in behavioral neuroscience · 2021Article
- Current Research on Complementary and Alternative Medicine (CAM) in the Treatment of Major Depressive Disorder: An Evidence-Based Review.Advances in experimental medicine and biology · 2021Review
- Impact of multidimensional interventions on quality of life and depression among older adults in a primary care setting in Brazil: a quasi-experimental study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2020Article
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe undertook a randomized controlled trial to assess the efficacy of group-based behavioral activation with mindfulness (BAM) for treating subthreshold depression in primary care in Hong Kong.
methodsWe recruited adult patients aged 18 years or older with subthreshold depression from public primary care clinics and randomly assigned them to a BAM intervention group or a usual care group. The BAM group was provided with eight 2-hour weekly BAM sessions by trained allied health care workers. Patients in the usual care group received usual medical care with no additional psychological interventions. The primary outcome was depressive symptoms measured by the Beck Depression Inventory-II at 12 months. Secondary outcomes included incidence of major depressive disorder at 12 months. We assessed quality of life, activity and circumstances change, functional impairment, and anxiety at baseline, end of intervention, 5 months, and 12 months.
resultsWe randomly allocated 115 patients to the BAM intervention and 116 patients to usual care. At 12 months, compared with usual care peers, BAM patients had a slightly more favorable change in levels of depressive symptoms on the Beck Depression Inventory-II (between-group mean difference in score = -3.85; 95% CI, -6.36 to -1.34; Cohen
conclusionsGroup BAM appears to be efficacious for decreasing depressive symptoms and reducing the incidence of major depression among patients with subthreshold depression in primary care, although generalizability of our findings may be limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.