Evidence map›Paper›PMID 29531090›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Phosphorylation-induced unfolding regulates p19

Amit Kumar, Mohanraj Gopalswamy, Annika Wolf, David J Brockwell, Mechthild Hatzfeld, Jochen Balbach

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Cysteine thiol-to-sulfonate oxidation induces unfolding for the functional switching of the extracellular HMGB1 protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  13. Long non-coding RNATranslational cancer research · 2019
    Article
  14. International journal of molecular sciences · 2019
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Amit KumarBiophysics Group, Institute of Physics, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.ORCID 0000-0001-8391-6812
Mohanraj GopalswamyBiophysics Group, Institute of Physics, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.
Annika WolfDivision of Pathobiochemistry, Institute of Molecular Medicine, Martin Luther University Halle-Wittenberg, 06097 Halle (Saale), Germany.
David J BrockwellAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT Leeds, United Kingdom.ORCID 0000-0002-0802-5937
Mechthild HatzfeldDivision of Pathobiochemistry, Institute of Molecular Medicine, Martin Luther University Halle-Wittenberg, 06097 Halle (Saale), Germany.
Jochen BalbachBiophysics Group, Institute of Physics, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany; Jochen.Balbach@physik.uni-halle.de.
Martin Luther University Halle-Wittenberg · DEUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell cycle progression is tightly regulated by cyclin-dependent kinases (CDKs). The ankyrin-repeat protein p19

Indexed as

Protein UnfoldingCell CycleCell DivisionCyclin-Dependent Kinase Inhibitor p19HEK293 CellsHeLa CellsHumansModels, MolecularPhosphorylationProtein ConformationProteolysisSignal TransductionCyclin-Dependent Kinase Inhibitor p19cell cycleNMR spectroscopyp19INK4dprotein phosphorylationprotein unfolding

Identifiers

PMID29531090
PMCPMC5879693
OpenAlexW2793835951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.