Evidence map›Paper›PMID 29531078›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule.

Aneesh T Veetil, Maulik S Jani, Yamuna Krishnan

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Quantitative Chemical Imaging of Organelles.Accounts of chemical research · 2024
    Article
  2. Endocrine therapy resistance: what we know and future directions.Exploration of targeted anti-tumor therapy · 2022
    Review
  3. Robotic DNA Nanostructures.ACS synthetic biology · 2020
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Growing community of artificial molecular machinists.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aneesh T VeetilDepartment of Chemistry, University of Chicago, Chicago, IL 60637.
Maulik S JaniDepartment of Chemistry, University of Chicago, Chicago, IL 60637.
Yamuna KrishnanDepartment of Chemistry, University of Chicago, Chicago, IL 60637; yamuna@uchicago.edu.ORCID 0000-0001-5282-8852

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
NCATS NIH HHS UL1 TR000430
6 · The paper itself

Abstract

Membrane-initiated steroid signaling (MISS) is a recently discovered aspect of steroidal control over cell function that has proved highly challenging to study due to its rapidity and ultrasensitivity to the steroid trigger [Chow RWY, Handelsman DJ, Ng MKC (2010)

Indexed as

Signal TransductionCalciumCell MembraneCells, CulturedDNAEstradiolEstrogen Receptor alphaHumansHuman Umbilical Vein Endothelial CellsModels, BiologicalNanocapsulesNanotechnologyNitric OxideSteroidsSulfhydryl CompoundsCalciumDNAEstradiolEstrogen Receptor alphaNanocapsulesNitric OxideSteroidsSulfhydryl Compoundscell signalingDNA nanotechnologyeNOSestradiollive imaging

Identifiers

PMID29531078
PMCPMC6156627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.