ArticleProceedings of the National Academy of Sciences of the United States of America2018
Programmable RNA recognition using a CRISPR-associated Argonaute.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed, 49 citations in OpenAlex.
- A DNA-guided prokaryotic argonaute enables programmable RNA cleavage for sequencing and quality control ofMolecular therapy. Nucleic acids · 2026Article
- Specificity of DNA targeting by RNA-guided pAgo nucleases.Nucleic acids research · 2026Article
- A programmable pAgo nuclease with high activity and specificity for efficient DNA and RNA manipulation.Communications biology · 2025Article
- mRNA vaccines and SiRNAs targeting cancer immunotherapy: challenges and opportunities.Discover oncology · 2025Review
- Article
- Delivery of gene editing therapeutics.Nanomedicine : nanotechnology, biology, and medicine · 2023Review
- Argonaute protein-based nucleic acid detection technology.Frontiers in microbiology · 2023Review
- Article
- Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.Nature communications · 2022Article
- An Argonaute fromActa biochimica et biophysica Sinica · 2022Article
- Article
- Prokaryotic Argonaute Proteins as a Tool for Biotechnology.Molecular biology · 2022Article
- A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis.Nucleic acids research · 2021Article
- Expression and Functional Analysis of the Argonaute Protein ofBiomolecules · 2021Article
- Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence.Nucleic acids research · 2020Article
- Genome-wide DNA sampling by Ago nuclease from the cyanobacteriumRNA biology · 2020Article
- High-Speed Super-Resolution Imaging Using Protein-Assisted DNA-PAINT.Nano letters · 2020Article
- RNA-targeting CRISPR systems from metagenomic discovery to transcriptomic engineering.Nature cell biology · 2020Review
- Programmable RNA manipulation in living cells.Cellular and molecular life sciences : CMLS · 2019Review
- DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.Nucleic acids research · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Argonaute proteins (Agos) are present in all domains of life. Although the physiological function of eukaryotic Agos in regulating gene expression is well documented, the biological roles of many of their prokaryotic counterparts remain enigmatic. In some bacteria, Agos are associated with CRISPR (clustered regularly interspaced short palindromic repeats) loci and use noncanonical 5'-hydroxylated guide RNAs (gRNAs) for nucleic acid targeting. Here we show that using 5-bromo-2'-deoxyuridine (BrdU) as the 5' nucleotide of gRNAs stabilizes in vitro reconstituted CRISPR-associated
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