Trial reportThe Lancet. Global health2018
Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011-14 (EFECAB): a cluster-randomised controlled trial.
Trial report in The Lancet. Global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Neurocysticercosis control for primary epilepsy prevention: a systematic review.Pathogens and global health · 2022Pooled it
- A qualitative assessment of the context and enabling environment for the control of Taenia solium infections in endemic settings.PLoS neglected tropical diseases · 2021Pooled it
- Prevalence of neurocysticercosis and its characteristics among people with epileptic seizures and progressively worsening severe headaches in 60 villages in three provinces of Burkina Faso.PLoS neglected tropical diseases · 2026Trial
- Geographically Targeted Interventions versus Mass Drug Administration to Control Taenia solium Cysticercosis, Peru.Emerging infectious diseases · 2021Trial
- Impact of Health Education Interventions for Control ofPublic health challenges · 2025Review
- Knowledge, attitudes and practices taeniasis/cysticercosis caused by Taenia solium among students and professionals of Bioanalysis in Maracay, Venezuela, 2020Biomedica : revista del Instituto Nacional de Salud · 2025Article
- We outside: Modeling equity-centered, antiracist, community-driven partnerships in resident education.AEM education and training · 2024Article
- The Vicious Worm education tool improves the knowledge of community health workers on Taenia solium cysticercosis in Rwanda.PLoS neglected tropical diseases · 2024Article
- Community knowledge, attitudes and practices related to Taenia solium taeniosis and cysticercosis in Zambia.PLoS neglected tropical diseases · 2023Article
- Aggregation ofParasite epidemiology and control · 2023Review
- Geostatistical analysis of active human cysticercosis: Results of a large-scale study in 60 villages in Burkina Faso.PLoS neglected tropical diseases · 2023Article
- Innovative Research Offers New Hope for Managing African Swine Fever Better in Resource-Limited Smallholder Farming Settings: A Timely Update.Pathogens (Basel, Switzerland) · 2023Review
- Knowledge, attitudes and practices related to Taenia solium cysticercosis and taeniasis in Tanzania.BMC infectious diseases · 2022Article
- Spatial distribution and risk factors for human cysticercosis in Colombia.Parasites & vectors · 2021Article
- Data-driven analyses of behavioral strategies to eliminate cysticercosis in sub-Saharan Africa.PLoS neglected tropical diseases · 2021Article
- The Interplay Between Neuroinfections, the Immune System and Neurological Disorders: A Focus on Africa.Frontiers in immunology · 2021Review
- Maximising Societal Benefit From the Control of Neglected Zoonoses: Identifying Synergies and Trade-Offs in the Control ofFrontiers in veterinary science · 2021Review
- Effects of 'The Vicious Worm' educational software on Taenia solium knowledge among key pork supply chain workers in Zambia.PLoS neglected tropical diseases · 2020Article
- Perceptions and acceptability of piloted Taenia solium control and elimination interventions in two endemic communities in eastern Zambia.Transboundary and emerging diseases · 2020Article
- Taenia solium Cysticercosis and Its Impact in Neurological Disease.Clinical microbiology reviews · 2020Review
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Authors and funding
18 authors at 12 institutions in 5 countries.
Funding
Abstract
backgroundThe effectiveness of drug-free interventions in controlling human cysticercosis is not well known. We aimed to estimate the effectiveness of a community-based educational intervention in reducing the frequency of human cysticercosis in Burkina Faso.
methodsWe did a cluster-randomised controlled trial between 2011 and 2014. 60 eligible villages from three provinces (Boulkiemdé, Sanguié, and Nayala) were randomly allocated to the intervention or control group. Villages raising pigs, that were not a regional capital or located on a main road, that were more than 20 km from Ouagadougou or 5 km from one another, were eligible. In each village, 60 participants were asked for blood samples at baseline, 18 months later (before randomisation), and 18 months after randomisation. Villages were block randomised (1:1) by pig-raising department immediately after the pre-randomisation visit. The intervention aimed to improve knowledge of Taenia solium transmission and control through screening and structured discussion of a 52-min movie, and to increase community self-efficacy through a Self-esteem, Associative strengths, Resourcefulness, Action planning, Responsibility (SARAR) approach via the Participatory Hygiene and Sanitation Transformation (PHAST) model. The primary outcome was active cysticercosis, defined as the presence of circulating antigens detected by use of B158/B60 ELISA. Effectiveness measured at the village level was estimated by use of three Bayesian hierarchical models. This study is registered with ClinicalTrials.gov, number NCT0309339.
findingsTwo villages in the same randomisation block were excluded, resulting in a final sample size of 58 villages. Overall, the intervention tended towards a decrease in the cumulative incidence of active cysticercosis from baseline to after randomisation (adjusted cumulative incidence ratio 0·65, 95% Bayesian credible interval [95% CrI] 0·39-1·05) and a decrease in active cysticercosis prevalence from baseline to after randomisation (adjusted prevalence proportion ratio 0·84; 95% CrI 0·59-1·18). The intervention was shown to be effective in Nayala and Sanguié but not in Boulkiemdé.
interpretationCommunity-engaged participatory interventions can be effective at reducing the incidence and prevalence of cysticercosis in some low-resource settings.
fundingUS National Institutes of Health (National Institute of Neurological Disorders and Stroke, Fogarty International Center, and National Institute of General Medical Sciences).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.