Evidence map›Paper›PMID 29530086›Full record

ArticleBMC research notes2018

Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya.

Calleb George Onyango, Lilian Ogonda, Bernard Guyah, Peter Okoth, Clement Shiluli, Felix Humwa, Vallarie Opollo

Erratum issuedAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Calleb George OnyangoDepartment of Biomedical Science and Technology, Maseno University, Maseno, Kenya. calleb.onyango@yahoo.com.ORCID http://orcid.org/0000-0001-5743-6057
Lilian OgondaDepartment of Biomedical Science and Technology, Maseno University, Maseno, Kenya.
Bernard GuyahDepartment of Biomedical Science and Technology, Maseno University, Maseno, Kenya.
Peter OkothJaramogi Oginga Odinga Teaching and Referral Hospital, Kisumu, Kenya.
Clement ShiluliDepartment of Biomedical Science and Technology, Maseno University, Maseno, Kenya.
Felix HumwaCenter for Disease Control and Prevention, Kisumu, Kenya.
Vallarie OpolloCenter for Disease Control and Prevention, Kisumu, Kenya.

Funding

HIGHER EDUCATION LOAN BOARD (HELB) HELB/45/003/VL/
6 · The paper itself

Abstract

objectiveSince the implementation of a series of blood donation safety improvements in Kenya, information about seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in high HIV burden regions of Homabay, Kisumu and Siaya counties remain scanty. A cross-sectional study examining HIV, syphilis, hepatitis B and C virus sero-markers and associated determinants was conducted among voluntary blood donors. Their demographic characteristics and previous risk exposure were recorded in a pre-donation questionnaire, while blood samples collected were screened for hepatitis B, hepatitis C, human immunodeficiency viruses by ELISA and RPR (syphilis), then confirmed using CMIA.

resultsOverall TTIs seroprevalence was 114 (9.4%), distributed among HIV, HBV, HCV and syphilis at 14 (1.15%), 42 (3.46%), 39 (3.21%) and 19 (1.56%), respectively, with co-infections of 3 (0.25%). There were no significant differences in proportions distributions among demographic variables. However, high risk sex was significantly associated with higher odds of HBV infections [> 1 partner vs. 0-1 partner; odd ratio (OR) 2.60; 95% confidence interval (CI) 1.098-6.86; p = 0.046]. In conclusion, a substantial percentage of blood donors still harbor transfusion transmissible infections despite recent safety improvements with greater majority cases caused by HBV infections arising from previous exposure to high risk sex.

Indexed as

AdolescentAdultAgedBlood DonorsCross-Sectional StudiesFemaleHepatitis BHepatitis CHIV InfectionsHumansKenyaMaleMiddle AgedSeroepidemiologic StudiesSyphilisYoung AdultDonorsHBVHIVKenyaSeroprevalence

Identifiers

PMID29530086
PMCPMC5848540

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.