Evidence map›Paper›PMID 29530074›Full record

ArticleParasites & vectors2018

Trypanosoma cruzi load in synanthropic rodents from rural areas in Chile.

Esteban Yefi-Quinteros, Catalina Muñoz-San Martín, Antonella Bacigalupo, Juana P Correa, Pedro E Cattan

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  8. Lizards as Silent Hosts of Trypanosoma cruzi.Emerging infectious diseases · 2022
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  9. The Parasite Load ofMicroorganisms · 2022
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  11. Insects · 2022
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  12. Article
  13. Review
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  16. Article
  17. Frequency ofVeterinary medicine international · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Esteban Yefi-QuinterosLaboratorio de Ecología, Departamento de Ciencias Biológicas Animales, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile.
Catalina Muñoz-San MartínLaboratorio de Ecología, Departamento de Ciencias Biológicas Animales, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile.
Antonella BacigalupoLaboratorio de Ecología, Departamento de Ciencias Biológicas Animales, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile.
Juana P CorreaLaboratorio de Ecología Evolutiva, Departamento de Ciencias Ecológicas, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Pedro E CattanLaboratorio de Ecología, Departamento de Ciencias Biológicas Animales, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile. pcattan@uchile.cl.
University of Chile · CL

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1140650Fondo Nacional de Desarrollo Científico y Tecnológico 1170367Fondo Nacional de Desarrollo Científico y Tecnológico 3170799
6 · The paper itself

Abstract

backgroundTrypanosoma cruzi is the agent of Chagas disease, a major public health problem in Latin America. Many wild and domestic animals are naturally infected with T. cruzi; rodents are one of the groups which have been consistently detected infected in different countries. The aim of this work was to characterize blood T. cruzi load in naturally infected rodents from a Chagas disease endemic region in Chile.

methodsBaited traps were set in domestic and peridomestic areas of rural dwellings. The rodents were anesthetized and blood sampled; DNA was extracted and the parasite load was quantified by T. cruzi satellite DNA real-time PCR assays.

resultsSeventy-one rodents of four species, Rattus rattus, Mus musculus, Phyllotis darwini and Octodon degus, were captured; R. rattus was the most abundant species. Fifty-nine samples (83.1%) were T. cruzi-positive and the median value of the parasite load was 2.99 parasite equivalents (par-eq)/ml. The comparison of frequency of infection or parasite load by species showed no differences. However, one R. rattus presented very elevated parasitemia (1644 par-eq/ml).

conclusionsThe overall levels of parasitemia were similar to those found in humans in Chile. The high infection levels in exotic and endemic rodents very near to rural settlements increases their relevance as T. cruzi hosts.

Indexed as

AnimalsChagas DiseaseChileDisease ReservoirsDNA, ProtozoanEndemic DiseasesFemaleGenotypeHost-Parasite InteractionsMaleMiceOctodonParasite LoadParasitemiaRatsRodent DiseasesDNA, ProtozoanChagas diseaseHost-parasite relationsParasitemiaQuantitative real-time PCRRattus rattus

Identifiers

PMID29530074
PMCPMC5848452
OpenAlexW2792639797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.