Evidence map›Paper›PMID 29529909›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Incidence and Risk Factors for Overweight and Obesity after Initiation of Antiretroviral Therapy in Dar es Salaam, Tanzania.

Alexander Kintu, Enju Liu, Ellen Hertzmark, Donna Spiegelman, Rachel Margaret Zack, Aisa Muya, David Sando, Till Bärnighausen, Wafaie Fawzi

Abstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander Kintu1 Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Enju Liu2 Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Ellen Hertzmark2 Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Donna Spiegelman2 Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Rachel Margaret Zack3 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Aisa Muya5 Management and Development for Health, Dar es Salaam, Tanzania.
David Sando1 Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Till Bärnighausen1 Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Wafaie Fawzi1 Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

IMPLEMENTATION OF PROGRAMS FOR THE PREVENTION, CARE AND TREATMENT OF HIV/AIDS IN U2GPS001966 · PS · HARVARD SCHOOL OF PUBLIC HEALTH · PI FAWZI, WAFAIE W · 2010 to 2015
$13.0M
NCHHSTP CDC HHS U2G PS001966
6 · The paper itself

Abstract

objectiveTo describe the incidence of and risk factors for overweight and obesity following antiretroviral therapy (ART) initiation.

methodsWe used Cox proportional hazards models to investigate risk factors for incident overweight and obesity in 79 074 individuals aged 15 years or older who initiated ART in Dar es Salaam, Tanzania.

resultsTwenty-five percent of the patients became overweight and 10% became obese. The incidence rate of obesity was 3.2 per 100 person-years (95% confidence interval [CI]: 3.1-3.3) in patients who were of normal weight before starting ART and 22.6 per 100 person-years (95% CI: 21.9-23.3) in those who were overweight. Lower CD4 count was associated with a higher risk of overweight and obesity ( P value for trend < .0001).

conclusionThere is a high burden of overweight and obesity after starting ART, leading to proportions of these 2 conditions that are similar to those in the general population.

Indexed as

AdolescentAdultAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountFemaleHIV InfectionsHumansIncidenceMaleMiddle AgedObesityOverweightProportional Hazards ModelsRisk FactorsSex FactorsTanzaniaantiretroviral therapyincidenceobesityoverweightrisk factors

Identifiers

PMID29529909
PMCPMC6748468

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.