ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2018
Neural Correlates of Emotion Regulation and Adolescent Suicidal Ideation.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review of MRI Studies and the "Emotional paiN and social Disconnect (END)" Brain Model of Suicidal Behavior in Youth.Behavioural neurology · 2023Pooled it
- Functional alterations of the suicidal brain: a coordinate-based meta-analysis of functional imaging studies.Brain imaging and behavior · 2022Pooled it
- Neural Correlates Involved in Behavioral Metrics of Emotion Regulation and Suicidal Thoughts and Behaviors.Archives of suicide research : official journal of the International Academy for Suicide ResearchPooled it
- A prospective investigation of the relation between dysfunctional family communication and suicidal ideation severity in a clinical adolescent sample: A serial mediation model.Journal of affective disorders · 2022Trial
- Familial Risk and Resilience Moderate the Association Between Intolerance of Uncertainty and Youth Suicidal Ideation.Journal of clinical psychology · 2026Article
- Differential neural activation during reward processing in preadolescent suicidal ideation.Child psychiatry and human development · 2026Article
- Alexithymia and self-harm in depressed adolescents: the mediating role of resting-state functional connectivity of the ventral hippocampal-fusiform gyrus.Annals of general psychiatry · 2026Article
- Factors influencing suicidal ideation in Chinese adolescents with first-episode depressive disorder: a cross-sectional study.BMC psychology · 2026Article
- Exercise-induced anandamide-CB1R signaling and prefrontal-amygdala stress circuits in adolescent depression: a critical hypothesis-driven narrative review.Frontiers in psychiatry · 2026Review
- Exercise and Adolescent Flourishing: A Gender-Specific Chain Mediation Model Involving Mindfulness and Rumination.Psychology research and behavior management · 2026Article
- The mediating effect of emotion dysregulation on the relationship between childhood maltreatment and suicidal ideation in patients with depression.Frontiers in psychology · 2026Article
- Differentiating suicide risk in treatment-resistant depression: clinical and functional imaging correlates of suicidal ideation and attempt.NeuroImage. Clinical · 2026Article
- Understanding the emergence of suicidal thoughts and behaviors in adolescence from a brain and behavioral developmental perspective.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Electroconvulsive therapy modulates Fronto-temporal functional connectivity in adolescents with depression and suicidal ideation.Frontiers in neuroimaging · 2026Article
- Understanding suicide in sexual minority youth: neural reactivity to social cues as a moderating influence.Cognitive, affective & behavioral neuroscience · 2025Article
- Concurrent and Prospective Prediction of Suicidal Ideation in Adolescents Using Multimethod Data and Machine Learning: A Pilot Study.JAACAP open · 2025Article
- Mapping emotion-modulated inhibitory control in borderline personality features: a dimensional approach using the emotional Go/No-Go task with EEG.Borderline personality disorder and emotion dysregulation · 2025Article
- Psychoneuroimmunoendocrinological and neuroanatomical basis of suicidal behavior: potential therapeutic strategies with a focus on transcranial magnetic stimulation (TMS).Brain, behavior, & immunity - health · 2025Article
- Emotion Regulation and Neural Connectivity After Frustrative Non-Reward in Adolescents: The Moderating Role of Cognitive Flexibility.Developmental psychobiology · 2025Article
- Neuroimaging findings of adolescent depression: A review by the Research Domain Criteria (RDoC) framework.Psychiatry research. Neuroimaging · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundResearch on the neural correlates associated with risk for suicidal ideation (SI) has been limited, particularly in one increasingly at-risk group-adolescents. Previous research with adolescents indicates that poor emotion regulation skills are linked with SI, but these studies have not previously examined neural activation in service of emotion regulation between those with and without SI histories.
methodsHere we examine whether SI is associated with neural responses during an emotion regulation functional magnetic resonance imaging task in a group of adolescents (N = 49) 13 to 20 years of age (mean = 16.95).
resultsWhile there were no differences between youths with and without SI in self-reported emotional responses to negative pictures, youths with SI activated the dorsolateral prefrontal cortex more than youths without SI on trials in which they attempted to regulate their emotional responses compared with trials in which they passively viewed negative pictures. In contrast, during passive viewing of negative stimuli, youths with SI activated the dorsolateral prefrontal cortex, temporoparietal junction, and cerebellum less than same-age control subjects.
conclusionsThese findings were robust to control subjects for depression and adversity exposure and are consistent with the idea that youths with SI have disrupted emotion regulation, potentially related to differences in recruitment of top-down control regions. In contrast, youths without SI activated regions implicated in emotion regulation even when not directed to effortfully control their emotional response. This is the first study to examine neural function during emotion regulation as a potential neural correlate of risk for SI in adolescents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.