ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2018
Separable Effects of Childhood Maltreatment and Adult Adaptive Functioning on Amygdala Connectivity During Emotion Processing.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Emotion Recognition in Adults With a History of Childhood Maltreatment: A Systematic Review.Trauma, violence & abuse · 2023Pooled it
- The mediation role of gray matter volume in the relationship between childhood maltreatment and psychological resilience in adolescents with first-episode major depressive disorder.Translational psychiatry · 2024Article
- Functional neuroimaging of resilience to trauma: convergent evidence and challenges for future research.Psychological medicine · 2023Review
- Human emotion processing accuracy, negative biases, and fMRI activation are associated with childhood trauma.Frontiers in psychiatry · 2023Article
- Impact of childhood maltreatment and resilience on behavioral and neural patterns of inhibitory control during emotional distraction.Development and psychopathology · 2022Article
- Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD.Development and psychopathology · 2022Article
- Adoption and trauma: Risks, recovery, and the lived experience of adoption.Child abuse & neglect · 2022Article
- The Neurobiology of Infant Attachment-Trauma and Disruption of Parent-Infant Interactions.Frontiers in behavioral neuroscience · 2022Review
- Childhood maltreatment results in altered deactivation of reward processing circuits in depressed patients: A functional magnetic resonance imaging study of a facial emotion recognition task.Neurobiology of stress · 2021Article
- Transforming the paradigm of child welfare.Development and psychopathology · 2021Article
- Social Regulation of Negative Valence Systems During Development.Frontiers in systems neuroscience · 2021Review
- Early life stress and brain function: Activity and connectivity associated with processing emotion and reward.NeuroImage · 2020Review
- Childhood Maltreatment Alters the Neural Processing of Chemosensory Stress Signals.Frontiers in psychiatry · 2020Article
- During infant maltreatment, stress targets hippocampus, but stress with mother present targets amygdala and social behavior.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Childhood Maltreatment Disrupts Brain-Mediated Pathways Between Adolescent Maternal Relationship Quality and Positive Adult Outcomes.Child maltreatment · 2019Article
- Development of Threat Expression Following Infant Maltreatment: Infant and Adult Enhancement but Adolescent Attenuation.Frontiers in behavioral neuroscience · 2019Article
- Neurocognitive Precursors of Substance Misuse Corresponding to Risk, Resistance, and Resilience Pathways: Implications for Prevention Science.Frontiers in psychiatry · 2019Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIndividuals with a history of maltreatment show altered amygdala reactivity to emotional stimuli, atypical frontal regulatory control, and differences in frontolimbic connectivity compared with nonmaltreated controls. However, despite early trauma, many individuals who experience maltreatment show resilience or adaptive functioning in adulthood including positive social, educational, and occupational outcomes.
methodsThe present study used a psychophysiological interaction model to examine the effect of adult adaptive functioning on group differences between maltreated and nonmaltreated adults in task-based amygdala functional connectivity. The task used was a facial emotion-matching paradigm. Functional magnetic resonance imaging scans were collected from 41 adults with a history of substantiated childhood maltreatment and 39 nonmaltreated adults who were well matched on demographic variables, all of whom had been studied since childhood. Adaptive functioning was measured with a composite score of success on stage-salient developmental tasks.
resultsConsistent with previous research, we found differences in task-related amygdala functional connectivity between the maltreated and nonmaltreated groups. Effects were seen in the left hippocampus, right dorsolateral prefrontal cortex, dorsomedial prefrontal cortex, and right thalamus. However, when adult functioning was included in the model, maltreatment-related differences in amygdala connectivity were observed only in the hippocampus. Adult adaptive functioning independently predicted task-related amygdala connectivity in frontal and parietal regions across the entire sample.
conclusionsThese results suggest that frontolimbic functional connectivity is predicted by positive developmental adaptation in this high-risk population, regardless of maltreatment history, whereas intralimbic connectivity (amygdala and hippocampus) is more specifically associated with maltreatment history.
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