Evidence map›Paper›PMID 29529209›Full record

ArticleAmerican journal of hypertension2018

Handgrip Strength and Blood Pressure in Children and Adolescents: Evidence From NHANES 2011 to 2014.

Rui Zhang, Changwei Li, Tingting Liu, Liqiang Zheng, Shengxu Li

Registry-linked trialAbstract read
In one paragraph

Article in American journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06624358 (Physical Activity in Adolescents With Chronic Kidney Disease), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06624358 narecruitingnot on this mapstarted 2025, after this paper: background citation

Physical Activity in Adolescents With Chronic Kidney Disease

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2025 to 2028Enrolled100ConditionsChronic Kidney DiseasesArmsIncrease Physical Activity
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rui ZhangInstitute of Chronic Disease Surveillance, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, China.
Changwei LiDepartment of Epidemiology and Biostatistics, University of Georgia College of Public Health, Athens, Georgia, USA.
Tingting LiuDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Liqiang ZhengDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Shengxu LiDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Ning Liu · 2016 to 2026
$25.3M
Tulane Clinical Center for Chronic Renal Insufficiency Cohort StudyU01DK060963 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, JING, HAMM, L LEE · 2001 to 2025
$13.9M
NIDDK NIH HHS U01 DK060963NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

backgroundPrevious studies have reported that handgrip strength, a measure of muscular fitness, is associated with cardiovascular risk factors. However, the association of handgrip strength with blood pressure (BP) in children has been inconsistent. We tested the association of handgrip strength with systolic and diastolic BP in children and adolescents from the National Health and Nutrition Examination Survey (NHANES) 2011-2014.

methodsThe study included 3,929 participants aged 8-19 years who underwent a handgrip test. The sum of the maximum handgrip strength from both hands was used. General linear models were used to examine the associations between handgrip strength and the outcome variables.

resultsAfter adjustment for age, race, sex, body mass index, and physical activities, handgrip strength was significantly and positively associated with systolic (P < 0.0001) and diastolic (P = 0.01) BP. There was an increasing trend in systolic BP as handgrip strength increased from the bottom quartile to the top quartile, with 2.1 mm Hg difference between the top and the bottom quartiles (P for trend <0.0001). Similar results were observed for diastolic BP.

conclusionsMuscular fitness is positively associated with BP in children and adolescents. The implications and underlying mechanisms for these results need further examinations.

Indexed as

Blood PressureHand StrengthPhysical FitnessAdolescentAge FactorsCardiovascular DiseasesChildFemaleHealth StatusHumansMaleMuscle, SkeletalRisk FactorsUnited StatesYoung Adult

Identifiers

PMID29529209
PMCPMC5998948

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.