Evidence map›Paper›PMID 29528907›Full record

ArticleDiseases of the colon and rectum2018

Recurrence of Rectal Prolapse After Surgical Repair in Women With Pelvic Organ Prolapse.

Tatiana Catanzarite, Daniel D Klaristenfeld, Marco J Tomassi, Gisselle Zazueta-Damian, Marianna Alperin

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Diseases of the colon and rectum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Connective tissue and genetics in the pathogenesis of rectal prolapse: A scoping review.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tatiana CatanzariteDepartment of Reproductive Medicine, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California, San Diego, San Diego, California.
Daniel D KlaristenfeldDepartment of General Surgery, Kaiser Permanente, San Diego, California.
Marco J TomassiDepartment of General Surgery, Kaiser Permanente, San Diego, California.
Gisselle Zazueta-DamianDepartment of Obstetrics and Gynecology, Division of Urogynecology, Kaiser Permanente, San Diego, California.
Marianna AlperinDepartment of Reproductive Medicine, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California, San Diego, San Diego, California.
Kaiser Permanente San Diego Medical Center · USUniversity of California, San Diego · US

Funding

UC San Diego Womens Reproductive Health Research ProgramK12HD001259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CYNTHIA GYAMFI-BANNERMAN · 1999 to 2026
$9.1M
Mechanisms and Impact of Pregnancy-Induced Adaptations in Pelvic Floor MusclesR01HD092515 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA · 2017 to 2025
$4.0M
Impact of Aging on Structure and Function of Pelvic Floor MusclesR03AG050951 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA · 2016 to 2017
$233k
NIA NIH HHS R03 AG050951NICHD NIH HHS K12 HD001259NICHD NIH HHS R01 HD092515
6 · The paper itself

Abstract

backgroundPelvic organ prolapse is prevalent among women with rectal prolapse.

objectiveThis study aimed to determine whether clinically significant pelvic organ prolapse impacts rectal prolapse recurrence after surgical repair.

designA retrospective cohort.

settingThis study was performed at a single managed-care institution. PATIENTS: Consecutive women undergoing rectal prolapse repair between 2008 and 2016 were included.

interventionsThere were no interventions.

main outcome measuresFull-thickness rectal prolapse recurrence was compared between 4 groups: abdominal repair without pelvic organ prolapse (AR-POP); abdominal repair with pelvic organ prolapse (AR+POP); perineal repair without pelvic organ prolapse PR-POP; and perineal repair with pelvic organ prolapse (PR+POP). Recurrence-free period and hazard of recurrence were compared using Kaplan-Meier and Cox proportional hazards methods. To identify potential confounding risk factors for rectal prolapse recurrence, the characteristics of subjects with/without recurrence were compared with univariable and multivariable analyses.

resultsOverall, pelvic organ prolapse was present in 33% of 112 women and was more prevalent among subjects with rectal prolapse recurrence (52.4% vs 28.6%, p = 0.04). Median follow-up was 42.5 months; rectal prolapse recurrence occurred in 18.8% at a median of 9 months. The rate of recurrence and the recurrence-free period differed significantly between groups: AR-POP 3.8%, 95.7 months; AR+POP 13.0%, 86.9 months; PR-POP 34.8%, 42.1 months; PR+POP 57.1%, 23.7 months (p < 0.001). Compared with AR-POP the HR (95% CI) of rectal prolapse recurrence was 3.1 (0.5-18.5) for AR+POP; 14.7 (3.0-72.9) for PR-POP and 31.1 (6.2-154.5) for PR+POP. Compared with AR+POP, PR+POP had a shorter recurrence-free period (p < 0.001) and a higher hazard of recurrence (HR, 10.2; 95% CI, 2.1-49.3). LIMITATIONS: The retrospective design was a limitation of this study.

conclusionsPelvic organ prolapse was associated with a higher rectal prolapse recurrence rate and earlier recurrence in women undergoing perineal, but not abdominal, repairs. Multidisciplinary evaluation can facilitate individualized management of women with rectal prolapse. Abdominal repair should be considered in women with concomitant rectal and pelvic organ prolapse. See Video Abstract at http://links.lww.com/DCR/A513.

Indexed as

Digestive System Surgical ProceduresAdultAgedAged, 80 and overCase-Control StudiesCohort StudiesComorbidityFemaleHumansKaplan-Meier EstimateMiddle AgedPelvic Organ ProlapseProportional Hazards ModelsRectal ProlapseRectumRecurrence

Identifiers

PMID29528907
PMCPMC5992067
OpenAlexW2793069163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.