Evidence map›Paper›PMID 29528720›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2018

Patient, Treatment, and Health Care Utilization Variables Associated with Adherence to Metabolic Monitoring Practices in Children and Adolescents Taking Second-Generation Antipsychotics.

Mary Coughlin, Catherine Lindsay Goldie, Joan Tranmer, Sarosh Khalid-Khan, Deborah Tregunno

Open access · bronzeAbstract read
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Second-generation antipsychotics in children: Risks and monitoring needs.Canadian family physician Medecin de famille canadien · 2018
    Article
  9. Canadian family physician Medecin de famille canadien · 2018
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mary Coughlin1 Department of Health Sciences, School of Nursing, Queen's University, Kingston, Ontario.ORCID 0000-0002-2635-5075
Catherine Lindsay Goldie1 Department of Health Sciences, School of Nursing, Queen's University, Kingston, Ontario.
Joan Tranmer1 Department of Health Sciences, School of Nursing, Queen's University, Kingston, Ontario.
Sarosh Khalid-Khan2 Department of Psychiatry, Queen's University, Kingston, Ontario.
Deborah Tregunno1 Department of Health Sciences, School of Nursing, Queen's University, Kingston, Ontario.
Queen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChildren and adolescents with a range of psychiatric disorders are increasingly being prescribed atypical or second-generation antipsychotics (SGAs). While SGAs are effective at treating conduct and behavioural symptoms, they infer significant cardiometabolic risk. This study aims to explore what patient, treatment, and health care utilization variables are associated with adherence to Canadian Alliance for Monitoring Effectiveness and Safety of Antipsychotics in Children (CAMESA) metabolic monitoring guidelines.

methodA retrospective chart review of 294 children and adolescents accessing a large outpatient psychiatry setting within a 2-year study period (2014-2016) was conducted. Baseline and follow-up metabolic monitoring, demographic, treatment, and health care utilization variables were then assessed over a 1-year period of interest.

resultsMetabolic monitoring practices did not adhere to CAMESA guidelines and were very poor over the 1-year observation period. There were significant differences between children (ages 4-12 years, n = 99) and adolescents (ages 13-18 years, n = 195). In adolescents, factors associated with any baseline metabolic monitoring were a higher number of psychiatry visits (odds ratio [OR], 1.2; 95% confidence interval [CI], 1.10 to 1.41), longer duration of contact (OR, 14; 95% CI, 2.31 to 82.4), and use of other non-SGA medications (OR, 3.2; 95% CI, 1.17 to 8.94). Among children, having an emergency room visit (OR, 3.4; 95% CI, 1.01 to 11.71) and taking aripiprazole (OR, 7.4; 95% CI, 2.02 to 27.45) increased the odds of receiving baseline metabolic monitoring.

conclusionFindings from this study highlight the need for better metabolic monitoring for children and adolescents taking SGAs. Enhanced focus on opportunities for multidisciplinary collaboration is needed to improve the quality of care offered to this population.

Indexed as

AdolescentAntipsychotic AgentsChildChild, PreschoolDrug MonitoringDrug-Related Side Effects and Adverse ReactionsFemaleGuideline AdherenceHumansMaleMental DisordersMetabolic DiseasesPatient Acceptance of Health CareAntipsychotic Agentsantipsychotic agentschild psychiatrydrug monitoringevidence-based practiceguideline adherencemetabolic side effects of drugs and substancespatient safety

Identifiers

PMID29528720
PMCPMC5894916
OpenAlexW2789271417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.