ArticleMolecular biology and evolution2018
Extended and Continuous Decline in Effective Population Size Results in Low Genomic Diversity in the World's Rarest Hyena Species, the Brown Hyena.
Article in Molecular biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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50 citing papers in PubMed, 105 citations in OpenAlex.
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- Genome assembly and annotation of a deep-diving pinniped, the northern elephant seal (Mirounga angustirostris).The Journal of heredity · 2026Article
- The genomic impact of population connectivity and decline in Africa's elephants.Nature communications · 2026Article
- Predicting extinction risk of gibbons from genomes of extinct Yunnan lar gibbon.Genome biology · 2026Article
- The genome of the relict earless monitor lizard, Lanthanotus borneensis, and the Toxicofera hypothesis.BMC biology · 2026Article
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- Exceedingly low genetic diversity in snow leopards due to persistently small population size.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genomes of Galápagos Mockingbirds Reveal the Impact of Island Size and Past Demography on Inbreeding and Genetic Load in Contemporary Populations.Molecular ecology · 2025Article
- Parallel genetic adaptation amid a background of changing effective population sizes in divergent yellow perch (Proceedings. Biological sciences · 2025Article
- Genomic adaptation to small population size and saltwater consumption in the critically endangered Cat Ba langur.Nature communications · 2024Article
- A comparison of genomic diversity and demographic history of the North Atlantic and Southwest Atlantic southern right whales.Molecular ecology · 2024Article
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- The origins and diversification of Holarctic brown bear populations inferred from genomes of past and present populations.Proceedings. Biological sciences · 2024Article
- Four new genome sequences of the Pallas's cat (Frontiers in genetics · 2024Article
- Genomics of the relict species Baronia brevicornis sheds light on its demographic history and genome size evolution across swallowtail butterflies.G3 (Bethesda, Md.) · 2023Article
- Hybridization of Atlantic puffins in the Arctic coincides with 20th-century climate change.Science advances · 2023Article
- Pangolin Genomes Offer Key Insights and Resources for the World's Most Trafficked Wild Mammals.Molecular biology and evolution · 2023Article
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Authors and funding
11 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyenas (family Hyaenidae), as the sister group to cats (family Felidae), represent a deeply diverging branch within the cat-like carnivores (Feliformia). With an estimated population size of <10,000 individuals worldwide, the brown hyena (Parahyaena brunnea) represents the rarest of the four extant hyena species and has been listed as Near Threatened by the IUCN. Here, we report a high-coverage genome from a captive bred brown hyena and both mitochondrial and low-coverage nuclear genomes of 14 wild-caught brown hyena individuals from across southern Africa. We find that brown hyena harbor extremely low genetic diversity on both the mitochondrial and nuclear level, most likely resulting from a continuous and ongoing decline in effective population size that started ∼1 Ma and dramatically accelerated towards the end of the Pleistocene. Despite the strikingly low genetic diversity, we find no evidence of inbreeding within the captive bred individual and reveal phylogeographic structure, suggesting the existence of several potential subpopulations within the species.
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