Evidence map›Paper›PMID 29528286›Full record

ArticleeLife2018

Nociceptive interneurons control modular motor pathways to promote escape behavior in

Anita Burgos, Ken Honjo, Tomoko Ohyama, Cheng Sam Qian, Grace Ji-Eun Shin, Daryl M Gohl, Marion Silies, W Daniel Tracey, Marta Zlatic, Albert Cardona and 1 more

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. eLife · 2025
    Article
  13. Nociception inCold Spring Harbor protocols · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anita BurgosDepartment of Neuroscience, Columbia University Medical Center, New York, United States.ORCID https://orcid.org/0000-0003-4603-2086
Ken HonjoFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
Tomoko OhyamaDepartment of Biology, McGill University, Montreal, Canada.
Cheng Sam QianDepartment of Neuroscience, Columbia University Medical Center, New York, United States.ORCID http://orcid.org/0000-0002-2456-3153
Grace Ji-Eun ShinDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, United States.
Daryl M GohlUniversity of Minnesota Genomics Center, Minneapolis, United States.
Marion SiliesEuropean Neuroscience Institute Göttingen, Göttingen, Germany.
W Daniel TraceyThe Linda and Jack Gill Center for Biomolecular Science, Indiana University, Bloomington, United States.ORCID http://orcid.org/0000-0003-4666-8199
Marta ZlaticJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.
Albert CardonaJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID http://orcid.org/0000-0003-4941-6536
Wesley B GrueberDepartment of Neuroscience, Columbia University Medical Center, New York, United States.ORCID http://orcid.org/0000-0001-6751-256X

Funding

Dendritic Patterning by Interacting Extrinsic CuesR01NS061908 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GRUEBER, WESLEY B · 2008 to 2022
$5.2M
A Genome-Wide Analysis of Nociception Molecules, from Expression to FunctionR01GM086458 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI TRACEY, WILLIAM D · 2011 to 2020
$2.6M
A versatile system for cell-specific control of gene expression in the fly brainR24NS086564 · NINDS · STANFORD UNIVERSITY · PI CLANDININ, THOMAS ROBERT, GRUEBER, WESLEY B · 2014 to 2017
$1.0M
Dissection of neural circuitry underlying nociception in Drosophila larvaeF31NS090909 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BURGOS, ANITA · 2014 to 2016
$126k
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM086458NIH HHS GM086458NIH HHS NS061908NIH HHS NS086564NIH HHS NS090909-01NINDS NIH HHS F31 NS090909NINDS NIH HHS R01 NS061908NINDS NIH HHS R24 NS086564
6 · The paper itself

Abstract

Rapid and efficient escape behaviors in response to noxious sensory stimuli are essential for protection and survival. Yet, how noxious stimuli are transformed to coordinated escape behaviors remains poorly understood. In

Indexed as

AnimalsBehavior, AnimalDrosophila melanogasterEfferent PathwaysEscape ReactionInterneuronsLarvaNociceptorsbehaviorD. melanogasterinterneuronlarvaneurosciencenociceptionsensory circuitsensory neuron

Identifiers

PMID29528286
PMCPMC5869015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.