Evidence map›Paper›PMID 29528045›Full record

ArticleGates open research2017

The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014.

Emma Slaymaker, Estelle McLean, Alison Wringe, Clara Calvert, Milly Marston, Georges Reniers, Chodziwadziwa Whiteson Kabudula, Amelia Crampin, Alison Price, Denna Michael and 11 more

Open access · goldAbstract read
In one paragraph

Article in Gates open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 6 countries.

Emma SlaymakerDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0002-4941-5739
Estelle McLeanDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Alison WringeDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Clara CalvertDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Milly MarstonDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Georges ReniersDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Chodziwadziwa Whiteson KabudulaMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2000, South Africa.
Amelia CrampinDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Alison PriceDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Denna MichaelNational Institute for Medical Research, Mwanza, Tanzania.
Mark UrassaNational Institute for Medical Research, Mwanza, Tanzania.
Daniel KwaroKenya Medical Research Institute, Kisumu, Kenya.
Maquins SeweKenya Medical Research Institute, Kisumu, Kenya.
Jeffrey W EatonDepartment of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UK.ORCID https://orcid.org/0000-0001-7728-728X
Rebecca RheadDepartment of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UK.
Jessica Nakiyingi-MiiroMRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.
Tom LutaloRakai Health Sciences Program, Entebbe, Uganda.
Dorean NabukaluRakai Health Sciences Program, Entebbe, Uganda.
Kobus HerbstAfrica Health Research Institute, Durban, 4001, South Africa.ORCID https://orcid.org/0000-0002-5436-9386
Victoria HosegoodAfrica Health Research Institute, Durban, 4001, South Africa.ORCID https://orcid.org/0000-0002-2244-2518
Basia ZabaDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0003-2449-0983
University of London · GBLondon School of Hygiene & Tropical Medicine · GBAfrica Health Research Institute · ZAImperial College London · GBKenya Medical Research Institute · KENational Institute for Medical Research · TZRakai Health Sciences Program · UGUganda Virus Research Institute · UGUniversity of the Witwatersrand · ZA

Funding

Medical Research Council G0902143Wellcome Trust
6 · The paper itself

Abstract

Timely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards transmission of infection.  Reliable, population-based estimates of new infections are difficult to obtain for the generalised epidemics in sub-Saharan Africa.  Mortality data indicate disease burden and, if disaggregated along the continuum from diagnosis to treatment, can also reflect the coverage and quality of different HIV services.  Neither routine statistics nor observational clinical studies can estimate mortality prior to linkage to care nor following disengagement from care.  For this, population-based data are required. The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa brings together studies in Kenya, Malawi, South Africa, Tanzania, Uganda, and Zimbabwe.  Eight studies have the necessary data to estimate mortality by HIV status, and seven can estimate mortality at different stages of the HIV care continuum.  This data note describes a harmonised dataset containing anonymised individual-level information on survival by HIV status for adults aged 15 and above. Among PLHIV, the dataset provides information on survival during different periods: prior to diagnosis of infection; following diagnosis but before linkage to care; in pre-antiretroviral treatment (ART) care; in the first six months after ART initiation; among people continuously on ART for 6+ months; and among people who have ever interrupted ART.

Indexed as

Anti-retroviral therapyHIVHIV care continuumHIV incidenceLongitudinalMortalityPopulation basedSub-Saharan Africa

Identifiers

PMID29528045
PMCPMC5841576
OpenAlexW2767322673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.