Evidence map›Paper›PMID 29527813›Full record

ArticleLower urinary tract symptoms2019

Effect of lower urinary tract symptoms on the quality of life and sexual function of males in China, Taiwan, and South Korea: Subgroup analysis of a cross-sectional, population-based study.

Limin Liao, Yao-Chi Chuang, Shih-Ping Liu, Kyu-Sung Lee, Tag Keun Yoo, Romeo Chu, Budiwan Sumarsono, Jian-Ye Wang

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Lower urinary tract symptoms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07663344 (Prospective Feasibility Trial on MRI-TRUS Fusion Water Vapour Ablation for Benign Prostatic Hyperplasia), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07663344 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective Feasibility Trial on MRI-TRUS Fusion Water Vapour Ablation for Benign Prostatic Hyperplasia (STEAM-MAP 1 Study - Steam Therapy With MRI and AI-assisted Planning)

TypeinterventionalSponsorChinese University of Hong KongRan2026 to 2028Enrolled15ConditionsBenign Prostatic Hyperplasia (BPH)ArmsMRI-TRUS fusion-guided Rezūm therapy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Limin LiaoDepartment of Urology, China Rehabilitation Research Center, Capital Medical University, Beijing, China.
Yao-Chi ChuangDepartment of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0002-1468-3792
Shih-Ping LiuDepartment of Urology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.
Kyu-Sung LeeDepartment of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0003-0891-2488
Tag Keun YooDepartment of Urology, Eulji Medical Center, Eulji University School of Medicine, Seoul, South Korea.
Romeo ChuAstellas Pharma Singapore Pte Ltd, 5 Pemimpin Drive, #19-03 Seasons View, Singapore 576149.
Budiwan SumarsonoAstellas Pharma Singapore Pte Ltd, 5 Pemimpin Drive, #19-03 Seasons View, Singapore 576149.
Jian-Ye WangDepartment of Urology, Beijing Hospital, Beijing, China.
Astellas Pharma (China) · CNBeijing Hospital · CNCapital Medical University · CNChang Gung University · TWEulji University · KRNational Taiwan University Hospital · TWSamsung Medical Center · KR

Funding

Astellas Pharma Inc.
6 · The paper itself

Abstract

objectiveLower urinary tract symptoms (LUTS) in males can reduce patients' quality of life (QoL) and affect sexual function and satisfaction. Although this has been documented in the US, Canada, Germany, Italy, UK, and Sweden, data are limited on the effects of LUTS on QoL and sexual function in Asian men. The present subgroup analysis of an Internet-based survey correlated the incidence of male LUTS by severity and category with self-assessed QoL and sexual function and satisfaction measures.

methodsMales aged ≥40 years were randomly selected from consumer survey panels in China, Taiwan, and South Korea. LUTS were defined using the International Continence Society (ICS) 2002 symptom definitions; symptom severity was assessed by the International Prostate Symptom Score (IPSS). The effect of LUTS on QoL was assessed using Patient Perception of Bladder Condition (PPBC) and IPSS QoL scores. Sexual function and satisfaction were assessed using the International Index of Erectile Function (IIEF).

resultsMen with moderate-to-severe LUTS and overlap of voiding, storage, and post-micturition symptom categories reported dissatisfaction with their QoL and sexual function. LUTS severity was negatively correlated with IIEF scores. Overlap of LUTS categories had a greater effect on QoL and sexual satisfaction than the incidence of just 1 LUTS.

conclusionThe findings of the present study suggest that LUTS is prevalent in >60% of Asian males aged ≥40 years and is associated with reduced QoL and sexual function, particularly in those with overlap of LUTS categories and greater symptom severity.

Indexed as

Sexual BehaviorChinaHumansIncidenceLower Urinary Tract SymptomsMaleMiddle AgedQuality of LifeRepublic of KoreaSeverity of Illness IndexSexual Dysfunction, PhysiologicalTaiwanAsialower urinary tract symptomsmalequality of lifesexual satisfaction

Identifiers

PMID29527813
PMCPMC7379957
OpenAlexW2793040907

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.