Evidence map›Paper›PMID 29527596›Full record

ArticleThe Lancet. Planetary health2017

Association of air particulate pollution with bone loss over time and bone fracture risk: analysis of data from two independent studies.

Diddier Prada, Jia Zhong, Elena Colicino, Antonella Zanobetti, Joel Schwartz, Nicholas Dagincourt, Shona C Fang, Itai Kloog, Joseph M Zmuda, Michael Holick and 5 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet. Planetary health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Hypocalcemia and bone mineral density changes following denosumab treatment in end-stage renal disease patients: a meta-analysis of observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Air Pollution and Osteoporosis.Current osteoporosis reports · 2024
    Review
  11. Exposure to air pollution might decrease bone mineral density and increase the prevalence of osteoporosis: a Mendelian randomization study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
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  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Diddier PradaDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Jia ZhongDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Elena ColicinoDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Nicholas DagincourtNew England Research Institute, 480 Pleasant St, Watertown, MA, 02472, USA.
Shona C FangNew England Research Institute, 480 Pleasant St, Watertown, MA, 02472, USA.
Itai KloogDepartment of Geography and Environmental Development, Ben-Gurion University of the Negev, 663 Beer Sheva, Israel.
Joseph M ZmudaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Michael HolickSchool of Medicine Endocrinology, Diabetes, and Nutrition, Boston University, One Silber Way, Boston, MA, 02215, USA.
Luis A HerreraUnidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología - Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, 14080, Mexico.
Lifang HouInstitute for Public Health and Medicine, Northwestern University, Chicago, ILL, 60611, USA.
Francesca DominiciDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Benedetta BartaliNew England Research Institute, 480 Pleasant St, Watertown, MA, 02472, USA.
Andrea A BaccarelliDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Ave, Boston, MA, 02115, USA.
Harvard University · USNew England Research (United States) · USInstituto Nacional de Cancerología · MXBen-Gurion University of the Negev · ILBoston University · USColumbia University · USNorthwestern University · USUniversity of Pittsburgh · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Racial/Ethnic Disparities in Fall Risk and Bone Strength Among MenR01AG020727 · NIA · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI BARTALI, BENEDETTA · 2002 to 2013
$6.4M
Cardiovascular Health and Air Pollution: A National StudyR01ES024332 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2015 to 2018
$2.5M
Molecular and Epigenetic Mitochondriomics of Air Particles, Lead and CognitionR01ES021733 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA · 2012 to 2015
$2.4M
Early Exposure to Persistent Organic Pollutants, Breast Milk Extracellular Vesicles and Abnormal Cardiometabolic ProgrammingR21ES027087 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BACCARELLI, ANDREA, PRADA, DIDDIER GIOVANNI · 2016 to 2017
$438k
NIA NIH HHS R01 AG020727NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES021733NIEHS NIH HHS R01 ES024332NIEHS NIH HHS R21 ES027087
6 · The paper itself

Abstract

backgroundAir particulate matter (PM) is a ubiquitous environmental exposure associated with oxidation, inflammation, and age-related chronic disease. Whether PM is associated with loss of bone mineral density (BMD) and risk of bone fractures is undetermined.

methodsWe conducted two complementary studies of: (i) long-term PM <2.5 μm (PM

findingsIn the Medicare analysis, risk of bone fracture admissions at osteoporosis-related sites was greater in areas with higher PM

interpretationOur results suggest that poor air quality is a modifiable risk factor for bone fractures and osteoporosis, especially in low-income communities.

Identifiers

PMID29527596
PMCPMC5841468
OpenAlexW2767412527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.