ArticleChronic stress (Thousand Oaks, Calif.)
Intersection of stress and gender in association with transitions in past year DSM-5 substance use disorder diagnoses in the United States.
Article in Chronic stress (Thousand Oaks, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The trial behind it
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Who cites it
37 citing papers in PubMed.
- A lifestyle physical activity intervention for women in alcohol treatment: A pilot randomized controlled trial.Journal of substance use and addiction treatment · 2024Trial
- Evaluating a longitudinal mediation model of perceived stress, depressive symptoms, and substance use treatment outcomes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Trial
- Advancing models of PTSD-AUD comorbidity: protocol for a multimethod framework using genetics and ecological momentary assessment.European journal of psychotraumatology · 2026Article
- Sex-specific neural activation to stress and alcohol cues in high-risk drinkers: links between orbitofrontal circuits, alcohol craving, and future drinking.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Association of pandemic-era US county-level policies with adult health and health behaviors.SSM - population health · 2026Article
- The Moderating Role of Psychological Well-Being in the Relation Between Stressful Life Events and Common Mental Disorders in the General Population.Scandinavian journal of psychology · 2026Article
- Sex differences in the genetic and causal relationships between depression, smoking, and alcohol use: the role of socioeconomic status.Psychological medicine · 2026Article
- Polygenic risk moderation of stressful life events in alcohol use disorder severity.BMC psychiatry · 2026Article
- The Impact of a Registry-Based Environmental Risk Score on Episodes of Alcohol Use Disorder and Drug Use Disorder in Swedish National Samples.Journal of studies on alcohol and drugs · 2026Article
- Neuropeptide Y1 receptor expressing circuit from the central amygdala to lateral hypothalamus modulates binge-like ethanol consumption in a sex-dependent manner.Alcohol, clinical & experimental research · 2025Article
- Sex differences in the microglial response to stress and chronic alcohol exposure in mice.Biology of sex differences · 2025Article
- One-year ecological momentary assessment of alcohol use, mood, and stress among individuals with alcohol use disorder during SARS-CoV-2 pandemics: a gender-specific reflection.European archives of psychiatry and clinical neuroscience · 2025Observational
- Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder.Nature. Mental health · 2025Article
- Abusive consumption of alcoholic beverages: results from COVITEL, the Telephone Survey of Risk and Protective Factors for Noncommunicable Chronic Diseases, 2022 and 2023.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Article
- Biochemical changes precede affective and cognitive anomalies in aging adult C57BL/6J mice with a prior history of adolescent alcohol binge-drinking.Addiction biology · 2024Article
- Coping and Social Support in Relation to Minority Stress and Cigarette Smoking Among Lesbian, Gay, and Bisexual Veterans.Annals of LGBTQ public and population health · 2024Article
- Associations of Sexual Orientation-Related Minority and Military Stressors With Past-Year Cigarette Use Among Lesbian, Gay, and Bisexual Veterans.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- EZH2-dependent epigenetic reprogramming in the central nucleus of amygdala regulates adult anxiety in both sexes after adolescent alcohol exposure.Translational psychiatry · 2024Article
- Traumatic stress-enhanced alcohol drinking: Sex differences and animal model perspectives.Current addiction reports · 2024Article
- Mixed-methods analysis of satisfaction during a 12-session mindfulness-based intervention for women with a substance use disorder and trauma symptomatology.Frontiers in psychology · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundStress contributes to the development and maintenance of substance use disorders (SUD), with some research suggesting that the impact of stress on SUD is greater in women. However, this has yet to be evaluated in a national dataset, across major substances of abuse.
methodsUsing data from the newly available U.S. National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; Wave 3;
resultsHaving 2 or more stressful life events in the past year increased the odds of having a new AUD, TUD, CUD, and OUD (OR=3.14, 2.15, 5.52, and 3.06, respectively) or ongoing AUD, TUD, and CUD (OR=2.39, 2.62, and 2.95, respectively) compared to 0 or 1 stressful life event. A stress by gender interaction for new vs. absent AUD demonstrated that having 2 or more stressful life events was associated with increased odds of new AUD in men (OR=2.51) and even greater odds of new AUD in women (OR=3.94).
conclusionsResults highlight that stress is a robust factor in both men and women with new or ongoing substance use disorders, and that effective treatments for substance use should consider the role of stress in addiction etiology and maintenance. There was little evidence for gender differences in the role of stress on transitions in substance use disorders, except for the onset of alcohol use disorders. Given that rates of alcohol use disorders are increasing in women; the impact of stress needs to be considered.
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