ArticleNeuroImage. Clinical2018
Orbitofrontal sulcogyral morphology is a transdiagnostic indicator of brain dysfunction.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Genetic insights on the mechanisms of human cortical folding.bioRxiv : the preprint server for biology · 2026Article
- Variable Presence of an Evolutionarily New Brain Structure Is Related to Trait Impulsivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Emotion-related impulsivity is related to orbitofrontal cortical sulcation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity.bioRxiv : the preprint server for biology · 2024Article
- Emotion-related impulsivity is related to orbitofrontal cortical sulcation.bioRxiv : the preprint server for biology · 2024Article
- Patterns and predictors of orbitofrontal sulcogyral morphology in a nonclinical population.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Orbitofrontal sulcal patterns in catatonia.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- Fundamental functional differences between gyri and sulci: implications for brain function, cognition, and behavior.Psychoradiology · 2021Review
- Increased Heschl's Gyrus Duplication in Schizophrenia Spectrum Disorders: A Cross-Sectional MRI Study.Journal of personalized medicine · 2021Article
- Towards Deciphering the Fetal Foundation of Normal Cognition and Cognitive Symptoms From Sulcation of the Cortex.Frontiers in neuroanatomy · 2021Article
- Orbitofrontal sulcogyral morphology in patients with cocaine use disorder.Psychiatry research. Neuroimaging · 2020Article
- Orbitofrontal Sulcogyral Pattern as a Transdiagnostic Trait Marker of Early Neurodevelopment in the Social Brain.Clinical EEG and neuroscience · 2020Review
- The use of the orbitofrontal H-sulcus as a reference frame for value signals.The European journal of neuroscience · 2020Article
- Behavioural profiling of autism connectivity abnormalities.BJPsych open · 2020Article
- An evaluation of automated tracing for orbitofrontal cortex sulcogyral pattern typing.Journal of neuroscience methods · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atypical sulcogyral patterns in the orbitofrontal cortex (OFC) are associated with increased risk for schizophrenia, as well as with quantitative traits associated with schizophrenia, such as anhedonia. Here we conduct a cross-diagnostic comparison to assess whether atypical OFC sulcogyral patterns confer risk for multiple brain disorders. We examined structural images from 4 groups of adult participants (N = 189), including those diagnosed with schizophrenia (SZ; N = 49), bipolar disorder (BP; N = 46), attention deficit hyperactivity disorder (ADHD; N = 41), and controls (N = 53). OFC sulcogyral pattern types were determined based on the continuity of the medial and lateral orbitofrontal sulcus. Chi-square analysis was performed to compare the sulcogyral pattern frequency distributions between patient groups and controls. We find that both SZ and BP groups had atypical pattern distributions, with increased atypical pattern frequencies relative to controls in the left hemisphere, consistent with the overlapping clinical features and genetic etiology of these disorders (SZ: χ
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