Evidence map›Paper›PMID 29527490›Full record

ArticleNeuroImage. Clinical2018

Callous-unemotional traits and brain structure: Sex-specific effects in anterior insula of typically-developing youths.

Nora Maria Raschle, Willeke Martine Menks, Lynn Valérie Fehlbaum, Martin Steppan, Areti Smaragdi, Karen Gonzalez-Madruga, Jack Rogers, Roberta Clanton, Gregor Kohls, Anne Martinelli and 7 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  6. Cognitive Mechanisms Underlying Prosocial Decision Making in Callous-Unemotional Traits.Journal of psychopathology and behavioral assessment · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Nora Maria RaschleDepartment of Child and Adolescent Psychiatry, University of Basel, Psychiatric University Hospital, Basel, Switzerland. Electronic address: nora.raschle@upkbs.ch.
Willeke Martine MenksDepartment of Child and Adolescent Psychiatry, University of Basel, Psychiatric University Hospital, Basel, Switzerland.
Lynn Valérie FehlbaumDepartment of Child and Adolescent Psychiatry, University of Basel, Psychiatric University Hospital, Basel, Switzerland.
Martin SteppanDepartment of Child and Adolescent Psychiatry, University of Basel, Psychiatric University Hospital, Basel, Switzerland.
Areti SmaragdiAcademic Unit of Psychology, University of Southampton, Southampton, England, UK.
Karen Gonzalez-MadrugaAcademic Unit of Psychology, University of Southampton, Southampton, England, UK.
Jack RogersSchool of Psychology, University of Birmingham, Birmingham, England, UK.
Roberta ClantonSchool of Psychology, University of Birmingham, Birmingham, England, UK.
Gregor KohlsDepartment of Psychiatry, Psychosomatics and Psychotherapy, Child Neuropsychology Section, University Hospital Aachen, Germany.
Anne MartinelliDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Anka BernhardDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Kerstin KonradDepartment of Psychiatry, Psychosomatics and Psychotherapy, Child Neuropsychology Section, University Hospital Aachen, Germany; JARA-Brain Institute II, Molecular Neuroscience and Neuroimaging, RWTH Aachen & Research Centre Juelich, Germany.
Beate Herpertz-DahlmannDepartment of Psychiatry, Psychosomatics and Psychotherapy, Child Neuropsychology Section, University Hospital Aachen, Germany; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of the RWTH, Aachen, Germany.
Christine M FreitagDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Graeme FairchildDepartment of Psychology, University of Bath, Bath, UK.
Stephane A De BritoSchool of Psychology, University of Birmingham, Birmingham, England, UK.
Christina StadlerDepartment of Child and Adolescent Psychiatry, University of Basel, Psychiatric University Hospital, Basel, Switzerland.
University of Basel · CHGoethe University Frankfurt · DEUniversity of Birmingham · GBUniversitätsklinikum Aachen · DEUniversity of Southampton · GBBrain (Germany) · DEUniversity of Bath · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Callous-unemotional traits are characterized by a lack of empathy, a disregard for others' feelings and shallow or deficient affect, such as a lack of remorse or guilt. Neuroanatomical correlates of callous-unemotional traits have been demonstrated in clinical samples (i.e., adolescents with disruptive behavior disorders). However, it is unknown whether callous-unemotional traits are associated with neuroanatomical correlates within normative populations without clinical levels of aggression or antisocial behavior. Here we investigated the relationship between callous-unemotional traits and gray matter volume using voxel-based morphometry in a large sample of typically-developing boys and girls ( General scientific summary: This study suggests that callous-unemotional traits have a neuroanatomical correlate within typically developing boys, but not girls. Bilateral anterior insula volume explains up to 19% of the variance in callous-unemotional traits in boys.

Indexed as

EmotionsEmpathySex CharacteristicsAdolescentAntisocial Personality DisorderBrainChildConduct DisorderFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMalePsychiatric Status Rating ScalesPsychometricsRegression AnalysisCallous-unemotional traitsInsulaPediatric neuroimagingSex differencesVoxel-based morphometry

Identifiers

PMID29527490
PMCPMC5842751
OpenAlexW2773180637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.